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Assay of microtubule movement driven by single kinesin molecules.
Howard J, Hunt AJ, Baek S. Howard J, et al. Methods Cell Biol. 1993;39:137-47. doi: 10.1016/s0091-679x(08)60167-3. Methods Cell Biol. 1993. PMID: 8246794 Review. No abstract available.
Conformational changes during kinesin motility.
Schief WR, Howard J. Schief WR, et al. Curr Opin Cell Biol. 2001 Feb;13(1):19-28. doi: 10.1016/s0955-0674(00)00169-1. Curr Opin Cell Biol. 2001. PMID: 11163129 Review.
Kinesin's tail domain is an inhibitory regulator of the motor domain.
Coy DL, Hancock WO, Wagenbach M, Howard J. Coy DL, et al. Nat Cell Biol. 1999 Sep;1(5):288-92. doi: 10.1038/13001. Nat Cell Biol. 1999. PMID: 10559941
Processivity of the motor protein kinesin requires two heads.
Hancock WO, Howard J. Hancock WO, et al. J Cell Biol. 1998 Mar 23;140(6):1395-405. doi: 10.1083/jcb.140.6.1395. J Cell Biol. 1998. PMID: 9508772 Free PMC article.
Molecular motors: structural adaptations to cellular functions.
Howard J. Howard J. Nature. 1997 Oct 9;389(6651):561-7. doi: 10.1038/39247. Nature. 1997. PMID: 9335494
The movement of kinesin along microtubules.
Howard J. Howard J. Annu Rev Physiol. 1996;58:703-29. doi: 10.1146/annurev.ph.58.030196.003415. Annu Rev Physiol. 1996. PMID: 8815816 Review.
Is the lever arm of myosin a molecular elastic element?
Howard J, Spudich JA. Howard J, et al. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4462-4. Proc Natl Acad Sci U S A. 1996. PMID: 8633090 No abstract available.
Kinesin swivels to permit microtubule movement in any direction.
Hunt AJ, Howard J. Hunt AJ, et al. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11653-7. doi: 10.1073/pnas.90.24.11653. Proc Natl Acad Sci U S A. 1993. PMID: 8265603 Free PMC article.
The torsional stiffness of kinesin, (117 +/- 19) x 10(-24) N.m.rad-1 (mean +/- SEM), is so low that one kT of energy (approximately 4.1 x 10(-21) J at room temperature) is sufficient to twist a kinesin molecule through more than 360 degrees from its resting orientation. .. …
The torsional stiffness of kinesin, (117 +/- 19) x 10(-24) N.m.rad-1 (mean +/- SEM), is so low that one kT of energy (approximately 4.1 x 10 …
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