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Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel.
Goolaerts A, Roux J, Ganter MT, Shlyonsky V, Chraibi A, Stéphane R, Mies F, Matthay MA, Naeije R, Sariban-Sohraby S, Howard M, Pittet JF. Goolaerts A, et al. Among authors: howard m. Am J Respir Cell Mol Biol. 2010 Jul;43(1):99-108. doi: 10.1165/rcmb.2008-0472OC. Epub 2009 Aug 28. Am J Respir Cell Mol Biol. 2010. PMID: 19717814 Free PMC article.
Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability.
Ganter MT, Roux J, Su G, Lynch SV, Deutschman CS, Weiss YG, Christiaans SC, Myazawa B, Kipnis E, Wiener-Kronish JP, Howard M, Pittet JF. Ganter MT, et al. Among authors: howard m. Am J Respir Cell Mol Biol. 2009 Jan;40(1):108-18. doi: 10.1165/rcmb.2007-0454OC. Epub 2008 Aug 14. Am J Respir Cell Mol Biol. 2009. PMID: 18703797 Free PMC article.
Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism.
Roux J, Carles M, Koh H, Goolaerts A, Ganter MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF. Roux J, et al. Among authors: howard m. J Biol Chem. 2010 Feb 12;285(7):4278-90. doi: 10.1074/jbc.M109.036731. Epub 2009 Dec 8. J Biol Chem. 2010. PMID: 19996317 Free PMC article.
Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism.
Frank J, Roux J, Kawakatsu H, Su G, Dagenais A, Berthiaume Y, Howard M, Canessa CM, Fang X, Sheppard D, Matthay MA, Pittet JF. Frank J, et al. Among authors: howard m. J Biol Chem. 2003 Nov 7;278(45):43939-50. doi: 10.1074/jbc.M304882200. Epub 2003 Aug 20. J Biol Chem. 2003. PMID: 12930837
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