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Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.
Barber J, Al-Majdoub ZM, Couto N, Howard M, Elmorsi Y, Scotcher D, Alizai N, de Wildt S, Stader F, Sepp A, Rostami-Hodjegan A, Achour B. Barber J, et al. Among authors: howard m. Eur J Pharm Sci. 2023 Mar 1;182:106375. doi: 10.1016/j.ejps.2023.106375. Epub 2023 Jan 7. Eur J Pharm Sci. 2023. PMID: 36626943 Free article.
Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice.
El-Khateeb E, Vasilogianni AM, Alrubia S, Al-Majdoub ZM, Couto N, Howard M, Barber J, Rostami-Hodjegan A, Achour B. El-Khateeb E, et al. Among authors: howard m. Pharmacol Ther. 2019 Nov;203:107397. doi: 10.1016/j.pharmthera.2019.107397. Epub 2019 Jul 31. Pharmacol Ther. 2019. PMID: 31376433 Review.
Mass spectrometry-based abundance atlas of ABC transporters in human liver, gut, kidney, brain and skin.
Al-Majdoub ZM, Achour B, Couto N, Howard M, Elmorsi Y, Scotcher D, Alrubia S, El-Khateeb E, Vasilogianni AM, Alohali N, Neuhoff S, Schmitt L, Rostami-Hodjegan A, Barber J. Al-Majdoub ZM, et al. Among authors: howard m. FEBS Lett. 2020 Dec;594(23):4134-4150. doi: 10.1002/1873-3468.13982. Epub 2020 Dec 3. FEBS Lett. 2020. PMID: 33128234 Free PMC article.
Profiling the proximal proteome of the activated μ-opioid receptor.
Polacco BJ, Lobingier BT, Blythe EE, Abreu N, Khare P, Howard MK, Gonzalez-Hernandez AJ, Xu J, Li Q, Novy B, Naing ZZC, Shoichet BK, Coyote-Maestas W, Levitz J, Krogan NJ, Von Zastrow M, Hüttenhain R. Polacco BJ, et al. Among authors: howard mk. Nat Chem Biol. 2024 Mar 25. doi: 10.1038/s41589-024-01588-3. Online ahead of print. Nat Chem Biol. 2024. PMID: 38528119
2,659 results