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Recommendations for measuring HIV reservoir size in cure-directed clinical trials.
Abdel-Mohsen M, Richman D, Siliciano RF, Nussenzweig MC, Howell BJ, Martinez-Picado J, Chomont N, Bar KJ, Yu XG, Lichterfeld M, Alcami J, Hazuda D, Bushman F, Siliciano JD, Betts MR, Spivak AM, Planelles V, Hahn BH, Smith DM, Ho YC, Buzon MJ, Gaebler C, Paiardini M, Li Q, Estes JD, Hope TJ, Kostman J, Mounzer K, Caskey M, Fox L, Frank I, Riley JL, Tebas P, Montaner LJ; BEAT-HIV Delaney Collaboratory to Cure HIV-1 infection. Abdel-Mohsen M, et al. Among authors: howell bj. Nat Med. 2020 Sep;26(9):1339-1350. doi: 10.1038/s41591-020-1022-1. Epub 2020 Sep 7. Nat Med. 2020. PMID: 32895573 Free PMC article. Review.
Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Pereira Ribeiro S, Strongin Z, Soudeyns H, Ten-Caten F, Ghneim K, Pacheco Sanchez G, Xavier de Medeiros G, Del Rio Estrada PM, Pelletier AN, Hoang T, Nguyen K, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskovas CV, Wu G, Micci L, Ribeiro RM, Chan CN, Estes JD, Silvestri G, Gorman DM, Howell BJ, Hazuda DJ, Paiardini M, Sekaly RP. Pereira Ribeiro S, et al. Among authors: howell bj. Nat Immunol. 2024 Oct;25(10):1900-1912. doi: 10.1038/s41590-024-01952-4. Epub 2024 Sep 12. Nat Immunol. 2024. PMID: 39266691 Free PMC article.
Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
Pereira Ribeiro S, Strongin Z, Soudeyns H, Ten-Caten F, Ghneim K, Pacheco Sanchez G, Xavier de Medeiros G, Del Rio Estrada PM, Pelletier AN, Hoang T, Nguyen K, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskovas CV, Wu G, Micci L, Ribeiro RM, Chan CN, Estes JD, Silvestri G, Gorman DM, Howell BJ, Hazuda DJ, Paiardini M, Sekaly RP. Pereira Ribeiro S, et al. Among authors: howell bj. Nat Immunol. 2025 Mar;26(3):524. doi: 10.1038/s41590-025-02079-w. Nat Immunol. 2025. PMID: 39821151 Free PMC article. No abstract available.
Comparison of manual and automated ultrasensitive assays for residual HIV-1 in plasma from individuals on suppressive antiretroviral therapy.
Coco SB, Stone M, Deng X, Wang Y, Rountree W, Scianna SR, Montalvo L, Dimapasoc M, Stengelin M, Sigal G, Wu G, Howell BJ, Palmer S, Jennings C, Richman DD, Gorelick RJ, Laird GM, Martin A, Jacobs JL, Mellors JW, G Deeks S, Busch MP. Coco SB, et al. Among authors: howell bj. J Clin Microbiol. 2025 Dec 17;63(12):e0099525. doi: 10.1128/jcm.00995-25. Epub 2025 Nov 18. J Clin Microbiol. 2025. PMID: 41251360 Free PMC article.
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size.
Ghneim K, Ten-Caten F, Santana AC, Latif MB, Diaz-Dinamarca DA, García-Salum T, Del Rio Estrada PM, Sohal P, Strongin Z, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskovas CV, Wu G, Micci L, Martins Sieben LF, Lopes Gerum PC, Dos Santos J, Netea MG, van der Ven A, Silvestri G, Hazuda DJ, Gorman DM, Howell BJ, Sharma AA, Paiardini M, Soudeyns H, Pereira Ribeiro S, Sekaly RP. Ghneim K, et al. Among authors: howell bj. Nat Immunol. 2026 Apr;27(4):686-699. doi: 10.1038/s41590-026-02458-x. Epub 2026 Mar 20. Nat Immunol. 2026. PMID: 41862649 Free PMC article.
TGF-β mediates epigenetic control of innate antiviral responses and SIV reservoir size.
Ghneim K, Ten-Caten F, Santana AC, Latif MB, Dinamarca DAD, García-Salum T, Estrada PMDR, Sohal P, Strongin Z, Harper J, Jean S, Wallace C, Balderas R, Lifson JD, Raghunathan G, Rimmer E, Pastuskova C, Wu G, Micci L, Sieben LFM, Gerum PCL, Dos Santos J, Netea MG, van der Ven A, Silvestri G, Hazuda DJ, Gorman DM, Howell BJ, Sharma AA, Paiardini M, Soudeyns H, Ribeiro SP, Sekaly RP. Ghneim K, et al. Among authors: howell bj. Res Sq [Preprint]. 2025 Mar 19:rs.3.rs-5626892. doi: 10.21203/rs.3.rs-5626892/v1. Res Sq. 2025. Update in: Nat Immunol. 2026 Apr;27(4):686-699. doi: 10.1038/s41590-026-02458-x. PMID: 40166014 Free PMC article. Updated. Preprint.
Initial productive and latent HIV infections originate in vivo by infection of resting T cells.
Wietgrefe SW, Anderson J, Duan L, Southern PJ, Zuck P, Wu G, Howell BJ, Reilly C, Kroon E, Chottanapund S, Buranapraditkun S, Sacdalan C, Tulmethakaan N, Colby DJ, Chomchey N, Prueksakaew P, Pinyakorn S, Trichavaroj R, Mitchell JL, Trautmann L, Hsu D, Vasan S, Manasnayakorn S, de Souza M, Tovanabutra S, Schuetz A, Robb ML, Phanuphak N, Ananworanich J, Schacker TW, Haase AT; RV254/SEARCH 010 Study Team. Wietgrefe SW, et al. Among authors: howell bj. J Clin Invest. 2023 Nov 15;133(22):e171501. doi: 10.1172/JCI171501. J Clin Invest. 2023. PMID: 37733443 Free PMC article.
78 results