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Curcumin Combined with FOLFOX Chemotherapy Is Safe and Tolerable in Patients with Metastatic Colorectal Cancer in a Randomized Phase IIa Trial.

Howells LM, Iwuji COO, Irving GRB, Barber S, Walter H, Sidat Z, Griffin-Teall N, Singh R, Foreman N, Patel SR, Morgan B, Steward WP, Gescher A, Thomas AL, Brown K. Howells LM, et al. J Nutr. 2019 Jul 1;149(7):1133-1139. doi: 10.1093/jn/nxz029. J Nutr. 2019. PMID: 31132111 Free PMC article. Clinical Trial.

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Risk of cancer incidence and mortality associated with diabetes: A systematic review with trend analysis of 203 cohorts.

Ling S, Brown K, Miksza JK, Howells LM, Morrison A, Issa E, Yates T, Khunti K, Davies MJ, Zaccardi F. Ling S, et al. Among authors: howells lm. Nutr Metab Cardiovasc Dis. 2021 Jan 4;31(1):14-22. doi: 10.1016/j.numecd.2020.09.023. Epub 2020 Sep 25. Nutr Metab Cardiovasc Dis. 2021. PMID: 33223399

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The role of stromal fibroblasts in lung carcinogenesis: A target for chemoprevention?

Mahale J, Smagurauskaite G, Brown K, Thomas A, Howells LM. Mahale J, et al. Among authors: howells lm. Int J Cancer. 2016 Jan 1;138(1):30-44. doi: 10.1002/ijc.29447. Epub 2015 Feb 6. Int J Cancer. 2016. PMID: 25611701 Free article. Review.

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Pancreatic stellate cells and pancreas cancer: current perspectives and future strategies.

Haqq J, Howells LM, Garcea G, Metcalfe MS, Steward WP, Dennison AR. Haqq J, et al. Among authors: howells lm. Eur J Cancer. 2014 Oct;50(15):2570-82. doi: 10.1016/j.ejca.2014.06.021. Epub 2014 Aug 1. Eur J Cancer. 2014. PMID: 25091797 Review.

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Translating curcumin to the clinic for lung cancer prevention: evaluation of the preclinical evidence for its utility in primary, secondary, and tertiary prevention strategies.

Howells LM, Mahale J, Sale S, McVeigh L, Steward WP, Thomas A, Brown K. Howells LM, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):483-94. doi: 10.1124/jpet.114.216333. Epub 2014 Jun 17. J Pharmacol Exp Ther. 2014. PMID: 24939419 Free article. Review.

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Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals.

Howells LM, Moiseeva EP, Neal CP, Foreman BE, Andreadi CK, Sun YY, Hudson EA, Manson MM. Howells LM, et al. Acta Pharmacol Sin. 2007 Sep;28(9):1274-304. doi: 10.1111/j.1745-7254.2007.00690.x. Acta Pharmacol Sin. 2007. PMID: 17723163 Review.

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Determining the efficacy of dietary phytochemicals in cancer prevention.

Manson MM, Foreman BE, Howells LM, Moiseeva EP. Manson MM, et al. Among authors: howells lm. Biochem Soc Trans. 2007 Nov;35(Pt 5):1358-63. doi: 10.1042/BST0351358. Biochem Soc Trans. 2007. PMID: 17956351 Review.

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Inequalities in cancer screening, prevention and service engagement between UK ethnic minority groups.

Abraham S, Foreman N, Sidat Z, Sandhu P, Marrone D, Headley C, Akroyd C, Nicholson S, Brown K, Thomas A, Howells LM, Walter HS. Abraham S, et al. Among authors: howells lm. Br J Nurs. 2022 May 26;31(10):S14-S24. doi: 10.12968/bjon.2022.31.10.S14. Br J Nurs. 2022. PMID: 35648663 Review.

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Modulation of signal-transduction pathways by chemopreventive agents.

Manson MM, Holloway KA, Howells LM, Hudson EA, Plummer SM, Squires MS, Prigent SA. Manson MM, et al. Among authors: howells lm. Biochem Soc Trans. 2000 Feb;28(2):7-12. doi: 10.1042/bst0280007. Biochem Soc Trans. 2000. PMID: 10816090 Review.

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Increased mitochondrial proline metabolism sustains proliferation and survival of colorectal cancer cells.

Alaqbi SS, Burke L, Guterman I, Green C, West K, Palacios-Gallego R, Cai H, Alexandrou C, Myint NNM, Parrott E, Howells LM, Higgins JA, Jones DJL, Singh R, Britton RG, Tufarelli C, Thomas A, Rufini A. Alaqbi SS, et al. Among authors: howells lm. PLoS One. 2022 Feb 7;17(2):e0262364. doi: 10.1371/journal.pone.0262364. eCollection 2022. PLoS One. 2022. PMID: 35130302 Free PMC article.

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