Howells DW - Search Results

1

1,026 experimental treatments in acute stroke.

O'Collins VE, Macleod MR, Donnan GA, Horky LL, van der Worp BH, Howells DW. O'Collins VE, et al. Among authors: howells dw. Ann Neurol. 2006 Mar;59(3):467-77. doi: 10.1002/ana.20741. Ann Neurol. 2006. PMID: 16453316

2

Publication bias in reports of animal stroke studies leads to major overstatement of efficacy.

Sena ES, van der Worp HB, Bath PM, Howells DW, Macleod MR. Sena ES, et al. Among authors: howells dw. PLoS Biol. 2010 Mar 30;8(3):e1000344. doi: 10.1371/journal.pbio.1000344. PLoS Biol. 2010. PMID: 20361022 Free PMC article.

3

Bringing rigour to translational medicine.

Howells DW, Sena ES, Macleod MR. Howells DW, et al. Nat Rev Neurol. 2014 Jan;10(1):37-43. doi: 10.1038/nrneurol.2013.232. Epub 2013 Nov 19. Nat Rev Neurol. 2014. PMID: 24247324 Review.

4

How can we improve the pre-clinical development of drugs for stroke?

Sena E, van der Worp HB, Howells D, Macleod M. Sena E, et al. Trends Neurosci. 2007 Sep;30(9):433-9. doi: 10.1016/j.tins.2007.06.009. Epub 2007 Aug 31. Trends Neurosci. 2007. PMID: 17765332 Review.

5

Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials.

Rewell SS, Churilov L, Sidon TK, Aleksoska E, Cox SF, Macleod MR, Howells DW. Rewell SS, et al. Among authors: howells dw. PLoS One. 2017 Feb 9;12(2):e0171688. doi: 10.1371/journal.pone.0171688. eCollection 2017. PLoS One. 2017. PMID: 28182727 Free PMC article.

6

Fish oil diet associated with acute reperfusion related hemorrhage, and with reduced stroke-related sickness behaviors and motor impairment.

Pascoe MC, Howells DW, Crewther DP, Constantinou N, Carey LM, Rewell SS, Turchini GM, Kaur G, Crewther SG. Pascoe MC, et al. Among authors: howells dw. Front Neurol. 2014 Feb 6;5:14. doi: 10.3389/fneur.2014.00014. eCollection 2014. Front Neurol. 2014. PMID: 24567728 Free PMC article.

7

Human in vitro models of ischaemic stroke: a test bed for translation.

Antonic A, Sena ES, Donnan GA, Howells DW. Antonic A, et al. Among authors: howells dw. Transl Stroke Res. 2012 Sep;3(3):306-9. doi: 10.1007/s12975-012-0201-x. Epub 2012 Jul 21. Transl Stroke Res. 2012. PMID: 24323805 No abstract available.

8

Hypertension and experimental stroke therapies.

O'Collins VE, Donnan GA, Macleod MR, Howells DW. O'Collins VE, et al. Among authors: howells dw. J Cereb Blood Flow Metab. 2013 Aug;33(8):1141-7. doi: 10.1038/jcbfm.2013.88. Epub 2013 Jun 5. J Cereb Blood Flow Metab. 2013. PMID: 23736641 Free PMC article. Review.

9

History of animal models of stroke.

O'Collins VE, Donnan GA, Howells DW. O'Collins VE, et al. Among authors: howells dw. Int J Stroke. 2011 Feb;6(1):77-8. doi: 10.1111/j.1747-4949.2010.00543.x. Int J Stroke. 2011. PMID: 21205245

10

Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing.

O'Collins VE, Macleod MR, Cox SF, Van Raay L, Aleksoska E, Donnan GA, Howells DW. O'Collins VE, et al. Among authors: howells dw. J Cereb Blood Flow Metab. 2011 Mar;31(3):962-75. doi: 10.1038/jcbfm.2010.184. Epub 2010 Oct 27. J Cereb Blood Flow Metab. 2011. PMID: 20978519 Free PMC article. Review.

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