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Can animal models of disease reliably inform human studies?
van der Worp HB, Howells DW, Sena ES, Porritt MJ, Rewell S, O'Collins V, Macleod MR. van der Worp HB, et al. Among authors: howells dw. PLoS Med. 2010 Mar 30;7(3):e1000245. doi: 10.1371/journal.pmed.1000245. PLoS Med. 2010. PMID: 20361020 Free PMC article.
Identification and characterization of outcome measures reported in animal models of epilepsy: Protocol for a systematic review of the literature-A TASK2 report of the AES/ILAE Translational Task Force of the ILAE.
Simonato M, Iyengar S, Brooks-Kayal A, Collins S, Depaulis A, Howells DW, Jensen F, Liao J, Macleod MR, Patel M, Potschka H, Walker M, Whittemore V, Sena ES. Simonato M, et al. Among authors: howells dw. Epilepsia. 2017 Nov;58 Suppl 4:68-77. doi: 10.1111/epi.13908. Epilepsia. 2017. PMID: 29105071
Bringing rigour to translational medicine.
Howells DW, Sena ES, Macleod MR. Howells DW, et al. Nat Rev Neurol. 2014 Jan;10(1):37-43. doi: 10.1038/nrneurol.2013.232. Epub 2013 Nov 19. Nat Rev Neurol. 2014. PMID: 24247324 Review.
Meta-analysis of data from animal studies: a practical guide.
Vesterinen HM, Sena ES, Egan KJ, Hirst TC, Churolov L, Currie GL, Antonic A, Howells DW, Macleod MR. Vesterinen HM, et al. Among authors: howells dw. J Neurosci Methods. 2014 Jan 15;221:92-102. doi: 10.1016/j.jneumeth.2013.09.010. Epub 2013 Oct 4. J Neurosci Methods. 2014. PMID: 24099992
Hypothermia revisited: Impact of ischaemic duration and between experiment variability.
Rewell SS, Jeffreys AL, Sastra SA, Cox SF, Fernandez JA, Aleksoska E, van der Worp HB, Churilov L, Macleod MR, Howells DW. Rewell SS, et al. Among authors: howells dw. J Cereb Blood Flow Metab. 2017 Oct;37(10):3380-3390. doi: 10.1177/0271678X16688704. Epub 2017 Jan 13. J Cereb Blood Flow Metab. 2017. PMID: 28084873 Free PMC article.
Hypertension and experimental stroke therapies.
O'Collins VE, Donnan GA, Macleod MR, Howells DW. O'Collins VE, et al. Among authors: howells dw. J Cereb Blood Flow Metab. 2013 Aug;33(8):1141-7. doi: 10.1038/jcbfm.2013.88. Epub 2013 Jun 5. J Cereb Blood Flow Metab. 2013. PMID: 23736641 Free PMC article. Review.
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