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A potent and selective Kallikrein-5 inhibitor delivers high pharmacological activity in Netherton Syndrome patient skin.
Liddle J, Beneton V, Benson M, Bingham R, Bouillot A, Boullay AB, Brook E, Cryan J, Denis A, Edgar E, Ferrie A, Fouchet MH, Grillot D, Holmes DS, Howes A, Krysa G, Laroze A, Lennon M, McClure F, Moquette A, Nicodeme E, Santiago B, Santos L, Smith KJ, Thorpe JH, Thripp G, Trottet L, Walker AL, Ward SA, Wang Y, Wilson S, Pearce AC, Hovnanian A. Liddle J, et al. Among authors: howes a. J Invest Dermatol. 2021 Mar 17:S0022-202X(21)00994-5. doi: 10.1016/j.jid.2021.01.029. Online ahead of print. J Invest Dermatol. 2021. PMID: 33744298
Final 5-year findings from the phase 3 HELIOS study of ibrutinib plus bendamustine and rituximab in patients with relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma.
Fraser GAM, Chanan-Khan A, Demirkan F, Santucci Silva R, Grosicki S, Janssens A, Mayer J, Bartlett NL, Dilhuydy MS, Loscertales J, Avigdor A, Rule S, Samoilova O, Pavlovsky MA, Goy A, Mato A, Hallek M, Salman M, Tamegnon M, Sun S, Connor A, Nottage K, Schuier N, Balasubramanian S, Howes A, Cramer P. Fraser GAM, et al. Among authors: howes a. Leuk Lymphoma. 2020 Dec;61(13):3188-3197. doi: 10.1080/10428194.2020.1795159. Epub 2020 Aug 6. Leuk Lymphoma. 2020. PMID: 32762271
Assembly and regulation of the chlorhexidine-specific efflux pump AceI.
Bolla JR, Howes AC, Fiorentino F, Robinson CV. Bolla JR, et al. Among authors: howes ac. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17011-17018. doi: 10.1073/pnas.2003271117. Epub 2020 Jul 7. Proc Natl Acad Sci U S A. 2020. PMID: 32636271 Free PMC article.
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