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Avoiding the oligomeric state: αB-crystallin inhibits fragmentation and induces dissociation of apolipoprotein C-II amyloid fibrils.
Binger KJ, Ecroyd H, Yang S, Carver JA, Howlett GJ, Griffin MD. Binger KJ, et al. FASEB J. 2013 Mar;27(3):1214-22. doi: 10.1096/fj.12-220657. Epub 2012 Nov 16. FASEB J. 2013. PMID: 23159935
This work reveals previously unrecognized mechanisms of alphaB-c chaperone action in amyloid assembly and fibril dynamics, and provides a rationale for the in vivo colocalization of small heat-shock proteins with amyloid deposits.-Binger, K. J., Ecroyd, H., Yang, S., Carver, J. A …
This work reveals previously unrecognized mechanisms of alphaB-c chaperone action in amyloid assembly and fibril dynamics, and provides a ra …
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