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Antitumor efficacy and reduced toxicity using an anti-CD137 Probody therapeutic.
Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2025930118. doi: 10.1073/pnas.2025930118.
Proc Natl Acad Sci U S A. 2021.
PMID: 34172583
Free PMC article.
Conditional PD-1/PD-L1 Probody Therapeutics Induce Comparable Antitumor Immunity but Reduced Systemic Toxicity Compared with Traditional Anti-PD-1/PD-L1 Agents.
Assi HH, Wong C, Tipton KA, Mei L, Wong K, Razo J, Chan C, Howng B, Sagert J, Krimm M, Diep L, Jang A, Nguyen MT, Lapuyade N, Singson V, Villanueva R, Paidhungat M, Liu S, Rangan V, Vasiljeva O, West JW, Richardson JH, Irving B, Daniel D, Belvin M, Kavanaugh WM.
Assi HH, et al. Among authors: howng b.
Cancer Immunol Res. 2021 Dec;9(12):1451-1464. doi: 10.1158/2326-6066.CIR-21-0031. Epub 2021 Oct 11.
Cancer Immunol Res. 2021.
PMID: 34635485
Free PMC article.
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Probody Therapeutic Design of 89Zr-CX-072 Promotes Accumulation in PD-L1-Expressing Tumors Compared to Normal Murine Lymphoid Tissue.
Giesen D, Broer LN, Lub-de Hooge MN, Popova I, Howng B, Nguyen M, Vasiljeva O, de Vries EGE, Pool M.
Giesen D, et al. Among authors: howng b.
Clin Cancer Res. 2020 Aug 1;26(15):3999-4009. doi: 10.1158/1078-0432.CCR-19-3137. Epub 2020 Jan 17.
Clin Cancer Res. 2020.
PMID: 31953313
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The tumor targeting performance of anti-CD166 Probody drug conjugate CX-2009 and its parental derivatives as monitored by 89Zr-immuno-PET in xenograft bearing mice.
Chomet M, Schreurs M, Nguyen M, Howng B, Villanueva R, Krimm M, Vasiljeva O, van Dongen GAMS, Vugts DJ.
Chomet M, et al. Among authors: howng b.
Theranostics. 2020 Apr 27;10(13):5815-5828. doi: 10.7150/thno.44334. eCollection 2020.
Theranostics. 2020.
PMID: 32483421
Free PMC article.
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Novel Ex Vivo Zymography Approach for Assessment of Protease Activity in Tissues with Activatable Antibodies.
Howng B, Winter MB, LePage C, Popova I, Krimm M, Vasiljeva O.
Howng B, et al.
Pharmaceutics. 2021 Sep 2;13(9):1390. doi: 10.3390/pharmaceutics13091390.
Pharmaceutics. 2021.
PMID: 34575469
Free PMC article.
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