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Reduced nephron number and glomerulomegaly in Australian Aborigines: a group at high risk for renal disease and hypertension.
Hoy WE, Hughson MD, Singh GR, Douglas-Denton R, Bertram JF. Hoy WE, et al. Kidney Int. 2006 Jul;70(1):104-10. doi: 10.1038/sj.ki.5000397. Epub 2006 May 24. Kidney Int. 2006. PMID: 16723986
We compared kidney findings in Aboriginal and non-Aboriginal people in one remote region. Glomerular number and mean glomerular volume were estimated with the disector/fractionator combination in the right kidney of 19 Aborigines and 24 non-Aboriginal people undergoing for
We compared kidney findings in Aboriginal and non-Aboriginal people in one remote region. Glomerular number and mean glomerular volum
New insights on glomerular hyperfiltration: a Japanese autopsy study.
Kanzaki G, Puelles VG, Cullen-McEwen LA, Hoy WE, Okabayashi Y, Tsuboi N, Shimizu A, Denton KM, Hughson MD, Yokoo T, Bertram JF. Kanzaki G, et al. JCI Insight. 2017 Oct 5;2(19):e94334. doi: 10.1172/jci.insight.94334. JCI Insight. 2017. PMID: 28978800 Free PMC article.
We estimated total nephron (glomerular) number (NglomTOTAL) as well as numbers of nonsclerosed (NglomNSG) and globally sclerosed glomeruli (NglomGSG), and the mean volume of nonsclerosed glomeruli (VglomNSG) in Japanese normotensive, hypertensive, and CKD subjects and inve
We estimated total nephron (glomerular) number (NglomTOTAL) as well as numbers of nonsclerosed (NglomNSG) and globally sclerosed glom
Design-based stereological methods for estimating numbers of glomerular podocytes.
Puelles VG, Douglas-Denton RN, Cullen-McEwen L, McNamara BJ, Salih F, Li J, Hughson MD, Hoy WE, Nyengaard JR, Bertram JF. Puelles VG, et al. Ann Anat. 2014 Jan;196(1):48-56. doi: 10.1016/j.aanat.2013.04.007. Epub 2013 May 28. Ann Anat. 2014. PMID: 23845787 Review.
Here we present new design-based stereological methods for estimating podocyte number in individual glomeruli of known volume, and in average glomeruli. ...
Here we present new design-based stereological methods for estimating podocyte number in individual glomeruli of known volume, and in …
Towards a definition of glomerulomegaly: clinical-pathological and methodological considerations.
Hughson MD, Hoy WE, Douglas-Denton RN, Zimanyi MA, Bertram JF. Hughson MD, et al. Nephrol Dial Transplant. 2011 Jul;26(7):2202-8. doi: 10.1093/ndt/gfq688. Epub 2010 Nov 29. Nephrol Dial Transplant. 2011. PMID: 21115671 Free PMC article.
Associations of glomerular number and birth weight with clinicopathological features of African Americans and whites.
Hughson MD, Gobe GC, Hoy WE, Manning RD Jr, Douglas-Denton R, Bertram JF. Hughson MD, et al. Am J Kidney Dis. 2008 Jul;52(1):18-28. doi: 10.1053/j.ajkd.2008.03.023. Epub 2008 Jun 2. Am J Kidney Dis. 2008. PMID: 18514988
Glomerular number and size in autopsy kidneys: the relationship to birth weight.
Hughson M, Farris AB 3rd, Douglas-Denton R, Hoy WE, Bertram JF. Hughson M, et al. Kidney Int. 2003 Jun;63(6):2113-22. doi: 10.1046/j.1523-1755.2003.00018.x. Kidney Int. 2003. PMID: 12753298
Nephron hypertrophy and glomerulosclerosis in normal donor kidneys.
Hoy WE, Bertram JF, Hughson MD. Hoy WE, et al. Clin J Am Soc Nephrol. 2014 Nov 7;9(11):1832-4. doi: 10.2215/CJN.08680814. Epub 2014 Oct 15. Clin J Am Soc Nephrol. 2014. PMID: 25318755 Free PMC article. No abstract available.
Human nephron number: implications for health and disease.
Bertram JF, Douglas-Denton RN, Diouf B, Hughson MD, Hoy WE. Bertram JF, et al. Pediatr Nephrol. 2011 Sep;26(9):1529-33. doi: 10.1007/s00467-011-1843-8. Epub 2011 May 22. Pediatr Nephrol. 2011. PMID: 21604189 Review.
For example, in a relatively small study of nephron number in 15 children <3 months of age, we found that nephron number ranged from approximately 250,000 to 1.1 million. ...
For example, in a relatively small study of nephron number in 15 children <3 months of age, we found that nephron number ranged fr …
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