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Preliminary results of pinpoint plantar long-wavelength infrared light irradiation on blood glucose, insulin and stress hormones in patients with type 2 diabetes mellitus.
Ryotokuji K, Ishimaru K, Kihara K, Namiki Y, Hozumi N. Ryotokuji K, et al. Among authors: hozumi n. Laser Ther. 2013;22(3):209-14. doi: 10.3136/islsm.22.209. Laser Ther. 2013. PMID: 24204095 Free PMC article.
Effect of pinpoint plantar long-wavelength infrared light irradiation on subcutaneous temperature and stress markers.
Ryotokuji K, Ishimaru K, Kihara K, Namiki Y, Hozumi N. Ryotokuji K, et al. Among authors: hozumi n. Laser Ther. 2013;22(2):93-102. doi: 10.3136/islsm.22.93. Epub 2013 Mar 31. Laser Ther. 2013. PMID: 24155554 Free PMC article.
CD72 stimulation modulates anti-IgM induced apoptotic signaling through the pathway of NF-kappaB, c-Myc and p27(Kip1).
Fujiwara N, Fusaki N, Hozumi N. Fujiwara N, et al. Among authors: hozumi n. Microbiol Immunol. 2004;48(1):59-66. doi: 10.1111/j.1348-0421.2004.tb03488.x. Microbiol Immunol. 2004. PMID: 14734859
1'-acetoxychavicol acetate is a novel nuclear factor kappaB inhibitor with significant activity against multiple myeloma in vitro and in vivo.
Ito K, Nakazato T, Xian MJ, Yamada T, Hozumi N, Murakami A, Ohigashi H, Ikeda Y, Kizaki M. Ito K, et al. Among authors: hozumi n. Cancer Res. 2005 May 15;65(10):4417-24. doi: 10.1158/0008-5472.CAN-05-0072. Cancer Res. 2005. PMID: 15899834
Catechin, a green tea component, rapidly induces apoptosis of myeloid leukemic cells via modulation of reactive oxygen species production in vitro and inhibits tumor growth in vivo.
Nakazato T, Ito K, Miyakawa Y, Kinjo K, Yamada T, Hozumi N, Ikeda Y, Kizaki M. Nakazato T, et al. Among authors: hozumi n. Haematologica. 2005 Mar;90(3):317-25. Haematologica. 2005. PMID: 15749663
Induction of apoptosis in human myeloid leukemic cells by 1'-acetoxychavicol acetate through a mitochondrial- and Fas-mediated dual mechanism.
Ito K, Nakazato T, Murakami A, Yamato K, Miyakawa Y, Yamada T, Hozumi N, Ohigashi H, Ikeda Y, Kizaki M. Ito K, et al. Among authors: hozumi n. Clin Cancer Res. 2004 Mar 15;10(6):2120-30. doi: 10.1158/1078-0432.ccr-1142-03. Clin Cancer Res. 2004. PMID: 15041733
Pretreatment with the thiol antioxidant N-acetyl-L-cysteine (NAC) did not inhibit caspase-8 activation, and the antagonistic anti-Fas antibody ZB4 did not block generation of reactive oxygen species, indicating that both pathways were involved independently in ACA-induced …
Pretreatment with the thiol antioxidant N-acetyl-L-cysteine (NAC) did not inhibit caspase-8 activation, and the antagonistic anti-Fas …
Induction of apoptosis in leukemic cells by homovanillic acid derivative, capsaicin, through oxidative stress: implication of phosphorylation of p53 at Ser-15 residue by reactive oxygen species.
Ito K, Nakazato T, Yamato K, Miyakawa Y, Yamada T, Hozumi N, Segawa K, Ikeda Y, Kizaki M. Ito K, et al. Among authors: hozumi n. Cancer Res. 2004 Feb 1;64(3):1071-8. doi: 10.1158/0008-5472.can-03-1670. Cancer Res. 2004. PMID: 14871840
Capsaicin (N-vanillyl-8-methyl-1-nonenamide) is a homovanillic acid derivative found in pungent fruits. Several investigators have reported the ability of capsaicin to inhibit events associated with the promotion of cancer. ...Pretreatment with the antioxidant N-ace …
Capsaicin (N-vanillyl-8-methyl-1-nonenamide) is a homovanillic acid derivative found in pungent fruits. Several investigators have re …
Involvement of Notch signaling in initiation of prechondrogenic condensation and nodule formation in limb bud micromass cultures.
Fujimaki R, Toyama Y, Hozumi N, Tezuka K. Fujimaki R, et al. Among authors: hozumi n. J Bone Miner Metab. 2006;24(3):191-8. doi: 10.1007/s00774-005-0671-y. J Bone Miner Metab. 2006. PMID: 16622731
We disrupted Notch signaling by using a gamma-secretase inhibitor, N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT), to analyze the function of Notch signaling in the culture system. ...
We disrupted Notch signaling by using a gamma-secretase inhibitor, N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-b …
Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses.
Shimura E, Hozumi N, Kanagawa O, Metzger D, Chambon P, Radtke F, Hirose S, Nakano N. Shimura E, et al. Among authors: hozumi n. Int Immunol. 2010 Apr;22(4):329-40. doi: 10.1093/intimm/dxq014. Epub 2010 Feb 25. Int Immunol. 2010. PMID: 20185432
A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals.
Fujiwara N, Hidano S, Mamada H, Ogasawara K, Kitamura D, Cooper MD, Hozumi N, Chen CL, Goitsuka R. Fujiwara N, et al. Among authors: hozumi n. Int Immunol. 2006 May;18(5):775-83. doi: 10.1093/intimm/dxl014. Epub 2006 Mar 31. Int Immunol. 2006. PMID: 16581823
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