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Causal Relationship Between Complement C3, C4, and Nonalcoholic Fatty Liver Disease: Bidirectional Mendelian Randomization Analysis.
Phenomics. 2021 Sep 23;1(5):211-221. doi: 10.1007/s43657-021-00023-0. eCollection 2021 Oct.
Phenomics. 2021.
PMID: 36939807
Free PMC article.
Per SD increase in C3 levels was significantly associated with higher risk of NAFLD (OR = 1.65, 95% CI 1.40, 1.94) in cross-sectional analysis while C4 was not (OR = 1.04, 95% CI 0.89, 1.21). Longitudinal analysis produced similar results (HR(C3) = 1.20, 95% CI 1.02 …
Per SD increase in C3 levels was significantly associated with higher risk of NAFLD (OR = 1.65, 95% CI 1.40, 1.94) in cross-sectional analys …
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