Hrycyna CA - Search Results

1

Oligomerization of the human ABC transporter ABCG2: evaluation of the native protein and chimeric dimers.

Bhatia A, Schäfer HJ, Hrycyna CA. Bhatia A, et al. Among authors: hrycyna ca. Biochemistry. 2005 Aug 16;44(32):10893-904. doi: 10.1021/bi0503807. Biochemistry. 2005. PMID: 16086592

2

Tools for eradicating HIV in the brain: prodrug dimeric inhibitors of P-gp.

Chmielewski J, Hrycyna C. Chmielewski J, et al. Ther Deliv. 2012 Jun;3(6):689-92. doi: 10.4155/tde.12.49. Ther Deliv. 2012. PMID: 22838065

3

Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution.

Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Takenaka K, et al. Among authors: hrycyna ca. Cancer Res. 2007 Jul 15;67(14):6965-72. doi: 10.1158/0008-5472.CAN-06-4720. Cancer Res. 2007. PMID: 17638908

4

Recombinant synthesis of human ABCG2 expressed in the yeast Saccharomyces cerevisiae: an experimental methodological study.

Jacobs A, Emmert D, Wieschrath S, Hrycyna CA, Wiese M. Jacobs A, et al. Among authors: hrycyna ca. Protein J. 2011 Mar;30(3):201-11. doi: 10.1007/s10930-011-9321-5. Protein J. 2011. PMID: 21424391

5

Dual inhibitors of the human blood-brain barrier drug efflux transporters P-glycoprotein and ABCG2 based on the antiviral azidothymidine.

Namanja-Magliano HA, Bohn K, Agrawal N, Willoughby ME, Hrycyna CA, Chmielewski J. Namanja-Magliano HA, et al. Among authors: hrycyna ca. Bioorg Med Chem. 2017 Oct 1;25(19):5128-5132. doi: 10.1016/j.bmc.2017.07.001. Epub 2017 Jul 6. Bioorg Med Chem. 2017. PMID: 28712845

6

Click chemistry-derived bivalent quinine inhibitors of P-glycoprotein-mediated cellular efflux.

Kuriakose J, Hrycyna CA, Chmielewski J. Kuriakose J, et al. Among authors: hrycyna ca. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4410-2. doi: 10.1016/j.bmcl.2012.04.125. Epub 2012 May 4. Bioorg Med Chem Lett. 2012. PMID: 22632934

7

Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers.

Namanja HA, Emmert D, Davis DA, Campos C, Miller DS, Hrycyna CA, Chmielewski J. Namanja HA, et al. Among authors: hrycyna ca. J Am Chem Soc. 2012 Feb 15;134(6):2976-80. doi: 10.1021/ja206867t. Epub 2011 Sep 9. J Am Chem Soc. 2012. PMID: 21866921 Free PMC article.

8

Inhibition of human P-glycoprotein transport and substrate binding using a galantamine dimer.

Namanja HA, Emmert D, Pires MM, Hrycyna CA, Chmielewski J. Namanja HA, et al. Among authors: hrycyna ca. Biochem Biophys Res Commun. 2009 Oct 30;388(4):672-6. doi: 10.1016/j.bbrc.2009.08.056. Epub 2009 Aug 14. Biochem Biophys Res Commun. 2009. PMID: 19683513 Free PMC article.

9

Inhibition of P-glycoprotein-mediated paclitaxel resistance by reversibly linked quinine homodimers.

Pires MM, Emmert D, Hrycyna CA, Chmielewski J. Pires MM, et al. Among authors: hrycyna ca. Mol Pharmacol. 2009 Jan;75(1):92-100. doi: 10.1124/mol.108.050492. Epub 2008 Oct 22. Mol Pharmacol. 2009. PMID: 18945821 Free PMC article.

10

Bivalent probes of the human multidrug transporter P-glycoprotein.

Pires MM, Hrycyna CA, Chmielewski J. Pires MM, et al. Among authors: hrycyna ca. Biochemistry. 2006 Sep 26;45(38):11695-702. doi: 10.1021/bi0608109. Biochemistry. 2006. PMID: 16981729

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