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A mouse model for spinal muscular atrophy.

Hsieh-Li HM, Chang JG, Jong YJ, Wu MH, Wang NM, Tsai CH, Li H. Hsieh-Li HM, et al. Nat Genet. 2000 Jan;24(1):66-70. doi: 10.1038/71709. Nat Genet. 2000. PMID: 10615130

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Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases.

Chung YH, Lin CW, Huang HY, Chen SL, Huang HJ, Sun YC, Lee GC, Lee-Chen GJ, Chang YC, Hsieh-Li HM. Chung YH, et al. Among authors: hsieh li hm. J Mol Neurosci. 2020 Jul;70(7):1140-1152. doi: 10.1007/s12031-020-01521-y. Epub 2020 Mar 13. J Mol Neurosci. 2020. PMID: 32170713

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Neuroimaging Spectrum at Pre-, Early, and Late Symptomatic Stages of SCA17 Mice.

Chen CC, Yao NW, Lin CW, Su WS, Wu CT, Chang C, Hsieh-Li HM. Chen CC, et al. Among authors: hsieh li hm. Cerebellum. 2020 Aug;19(4):487-500. doi: 10.1007/s12311-020-01127-5. Cerebellum. 2020. PMID: 32270465

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ERK activation precedes Purkinje cell loss in mice with Spinocerebellar ataxia type 17.

Lin CW, Fan CH, Chang YC, Hsieh-Li HM. Lin CW, et al. Among authors: hsieh li hm. Neurosci Lett. 2020 Nov 1;738:135337. doi: 10.1016/j.neulet.2020.135337. Epub 2020 Aug 30. Neurosci Lett. 2020. PMID: 32877710

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Puerariae Radix Prevents Anxiety and Cognitive Deficits in Mice Under Oligomeric Aβ-Induced Stress.

Huang HJ, Huang CY, Lee M, Lin JY, Hsieh-Li HM. Huang HJ, et al. Among authors: hsieh li hm. Am J Chin Med. 2019;47(7):1459-1481. doi: 10.1142/S0192415X19500757. Am J Chin Med. 2019. PMID: 31752523

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Lactobacillus plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse models of Parkinson's disease.

Liao JF, Cheng YF, You ST, Kuo WC, Huang CW, Chiou JJ, Hsu CC, Hsieh-Li HM, Wang S, Tsai YC. Liao JF, et al. Among authors: hsieh li hm. Brain Behav Immun. 2020 Nov;90:26-46. doi: 10.1016/j.bbi.2020.07.036. Epub 2020 Jul 30. Brain Behav Immun. 2020. PMID: 32739365 Free article.

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Survival Motor Neuron Protein Participates in Mouse Germ Cell Development and Spermatogonium Maintenance.

Chang WF, Xu J, Lin TY, Hsu J, Hsieh-Li HM, Hwu YM, Liu JL, Lu CH, Sung LY. Chang WF, et al. Among authors: hsieh li hm. Int J Mol Sci. 2020 Jan 25;21(3):794. doi: 10.3390/ijms21030794. Int J Mol Sci. 2020. PMID: 31991812 Free PMC article.

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LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer's disease.

Fan CH, Lin CW, Huang HJ, Lee-Chen GJ, Sun YC, Lin W, Chen CM, Chang KH, Su MT, Hsieh-Li HM. Fan CH, et al. Among authors: hsieh li hm. Psychopharmacology (Berl). 2020 Oct;237(10):3173-3190. doi: 10.1007/s00213-020-05602-z. Epub 2020 Aug 4. Psychopharmacology (Berl). 2020. PMID: 32748031

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Novel compound VB-037 inhibits Aβ aggregation and promotes neurite outgrowth through enhancement of HSP27 and reduction of P38 and JNK-mediated inflammation in cell models for Alzheimer's disease.

Chiu YJ, Hsieh YH, Lin TH, Lee GC, Hsieh-Li HM, Sun YC, Chen CM, Chang KH, Lee-Chen GJ. Chiu YJ, et al. Among authors: hsieh li hm. Neurochem Int. 2019 May;125:175-186. doi: 10.1016/j.neuint.2019.01.021. Epub 2019 Jan 29. Neurochem Int. 2019. PMID: 30707915

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Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models.

Chen CM, Chen WL, Hung CT, Lin TH, Lee MC, Chen IC, Lin CH, Chao CY, Wu YR, Chang KH, Hsieh-Li HM, Lee-Chen GJ. Chen CM, et al. Among authors: hsieh li hm. Aging (Albany NY). 2019 Feb 13;11(3):986-1007. doi: 10.18632/aging.101804. Aging (Albany NY). 2019. PMID: 30760647 Free PMC article.

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