Hsu B - Search Results

1

Sirukumab, a human anti-interleukin-6 monoclonal antibody: a randomised, 2-part (proof-of-concept and dose-finding), phase II study in patients with active rheumatoid arthritis despite methotrexate therapy.

Smolen JS, Weinblatt ME, Sheng S, Zhuang Y, Hsu B. Smolen JS, et al. Among authors: hsu b. Ann Rheum Dis. 2014 Sep;73(9):1616-25. doi: 10.1136/annrheumdis-2013-205137. Epub 2014 Apr 3. Ann Rheum Dis. 2014. PMID: 24699939 Free PMC article. Clinical Trial.

2

Efficacy and safety of monotherapy with sirukumab compared with adalimumab monotherapy in biologic-naïve patients with active rheumatoid arthritis (SIRROUND-H): a randomised, double-blind, parallel-group, multinational, 52-week, phase 3 study.

Taylor PC, Schiff MH, Wang Q, Jiang Y, Zhuang Y, Kurrasch R, Daga S, Rao R, Tak PP, Hsu B. Taylor PC, et al. Among authors: hsu b. Ann Rheum Dis. 2018 May;77(5):658-666. doi: 10.1136/annrheumdis-2017-212496. Epub 2018 Feb 26. Ann Rheum Dis. 2018. PMID: 29483080 Clinical Trial.

3

Confirmatory Population Pharmacokinetic Analysis for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin-6, in Patients With Moderately to Severely Active Rheumatoid Arthritis.

Xu Y, Hu C, Zhuang Y, Hsu B, Xu Z, Zhou H. Xu Y, et al. Among authors: hsu b. J Clin Pharmacol. 2018 Jul;58(7):939-951. doi: 10.1002/jcph.1101. Epub 2018 Mar 26. J Clin Pharmacol. 2018. PMID: 29578578 Clinical Trial.

4

Exposure-Response Modeling Analyses for Sirukumab, a Human Monoclonal Antibody Targeting Interleukin 6, in Patients With Moderately to Severely Active Rheumatoid Arthritis.

Xu Y, Hu C, Zhuang Y, Hsu B, Xu Z, Sharma A, Zhou H. Xu Y, et al. Among authors: hsu b. J Clin Pharmacol. 2018 Nov;58(11):1501-1515. doi: 10.1002/jcph.1272. Epub 2018 Jun 14. J Clin Pharmacol. 2018. PMID: 29901815 Clinical Trial.

5

Joint longitudinal model development: application to exposure-response modeling of ACR and DAS scores in rheumatoid arthritis patients treated with sirukumab.

Hu C, Xu Y, Zhuang Y, Hsu B, Sharma A, Xu Z, Zhang L, Zhou H. Hu C, et al. Among authors: hsu b. J Pharmacokinet Pharmacodyn. 2018 Oct;45(5):679-691. doi: 10.1007/s10928-018-9598-5. Epub 2018 Jun 30. J Pharmacokinet Pharmacodyn. 2018. PMID: 29961161 Clinical Trial.

6

Sirukumab for rheumatoid arthritis: the phase III SIRROUND-D study.

Takeuchi T, Thorne C, Karpouzas G, Sheng S, Xu W, Rao R, Fei K, Hsu B, Tak PP. Takeuchi T, et al. Among authors: hsu b. Ann Rheum Dis. 2017 Dec;76(12):2001-2008. doi: 10.1136/annrheumdis-2017-211328. Epub 2017 Aug 30. Ann Rheum Dis. 2017. PMID: 28855173 Free PMC article. Clinical Trial.

7

Investigating sirukumab for rheumatoid arthritis: 2-year results from the phase III SIRROUND-D study.

Thorne C, Takeuchi T, Karpouzas GA, Sheng S, Kurrasch R, Fei K, Hsu B. Thorne C, et al. Among authors: hsu b. RMD Open. 2018 Nov 16;4(2):e000731. doi: 10.1136/rmdopen-2018-000731. eCollection 2018. RMD Open. 2018. PMID: 30564449 Free PMC article.

8

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Treatment With Sirukumab (CNTO 136) in Patients With Active Lupus Nephritis.

Rovin BH, van Vollenhoven RF, Aranow C, Wagner C, Gordon R, Zhuang Y, Belkowski S, Hsu B. Rovin BH, et al. Among authors: hsu b. Arthritis Rheumatol. 2016 Sep;68(9):2174-83. doi: 10.1002/art.39722. Arthritis Rheumatol. 2016. PMID: 27110697 Free PMC article. Clinical Trial.

9

Golimumab 3-year safety update: an analysis of pooled data from the long-term extensions of randomised, double-blind, placebo-controlled trials conducted in patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis.

Kay J, Fleischmann R, Keystone E, Hsia EC, Hsu B, Mack M, Goldstein N, Braun J, Kavanaugh A. Kay J, et al. Among authors: hsu b. Ann Rheum Dis. 2015 Mar;74(3):538-46. doi: 10.1136/annrheumdis-2013-204195. Epub 2013 Dec 16. Ann Rheum Dis. 2015. PMID: 24344160 Free PMC article. Clinical Trial.

10

Sirukumab and adalimumab reduce power Doppler ultrasound signal in patients with rheumatoid arthritis by 4 weeks in a phase III trial.

Sweet K, Dasgupta B, de Vries D, Gourley I, Hsu B, Loza MJ, Taylor PC. Sweet K, et al. Among authors: hsu b. Ann Rheum Dis. 2019 Oct;78(10):1439-1441. doi: 10.1136/annrheumdis-2019-215183. Epub 2019 Apr 24. Ann Rheum Dis. 2019. PMID: 31018960 Clinical Trial. No abstract available.

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