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PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis.
Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, Ross CA, Masliah E, Evans RM, La Spada AR. Dickey AS, et al. Among authors: hsu cl. Sci Transl Med. 2017 Dec 6;9(419):eaal2332. doi: 10.1126/scitranslmed.aal2332. Sci Transl Med. 2017. PMID: 29212711 Free PMC article.
Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagy.
Dubinsky AN, Dastidar SG, Hsu CL, Zahra R, Djakovic SN, Duarte S, Esau CC, Spencer B, Ashe TD, Fischer KM, MacKenna DA, Sopher BL, Masliah E, Gaasterland T, Chau BN, Pereira de Almeida L, Morrison BE, La Spada AR. Dubinsky AN, et al. Among authors: hsu cl. Cell Metab. 2014 Oct 7;20(4):626-38. doi: 10.1016/j.cmet.2014.09.001. Cell Metab. 2014. PMID: 25295787 Free PMC article.
Alcohol, the gut microbiome, and liver disease.
Jew MH, Hsu CL. Jew MH, et al. Among authors: hsu cl. J Gastroenterol Hepatol. 2023 Aug;38(8):1205-1210. doi: 10.1111/jgh.16199. Epub 2023 Apr 25. J Gastroenterol Hepatol. 2023. PMID: 37096652 Review.
Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD.
Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R. Caussy C, et al. Aliment Pharmacol Ther. 2019 Jan;49(2):183-193. doi: 10.1111/apt.15035. Epub 2018 Dec 2. Aliment Pharmacol Ther. 2019. PMID: 30506692 Free PMC article.
Serum aryl hydrocarbon receptor activity is associated with survival in patients with alcohol-associated hepatitis.
Yamazaki T, Kouno T, Hsu CL, Hartmann P, Mayo S, Zhang X, Stärkel P, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS Jr, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Schnabl B; AlcHepNet Investigators. Yamazaki T, et al. Among authors: hsu cl. Hepatology. 2024 Feb 20. doi: 10.1097/HEP.0000000000000777. Online ahead of print. Hepatology. 2024. PMID: 38377466
737 results