Hsu LC - Search Results

1

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

Hsu LC, Park JM, Zhang K, Luo JL, Maeda S, Kaufman RJ, Eckmann L, Guiney DG, Karin M. Hsu LC, et al. Nature. 2004 Mar 18;428(6980):341-5. doi: 10.1038/nature02405. Nature. 2004. PMID: 15029200 Free article.

2

Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis.

Valledor AF, Hsu LC, Ogawa S, Sawka-Verhelle D, Karin M, Glass CK. Valledor AF, et al. Among authors: hsu lc. Proc Natl Acad Sci U S A. 2004 Dec 21;101(51):17813-8. doi: 10.1073/pnas.0407749101. Epub 2004 Dec 15. Proc Natl Acad Sci U S A. 2004. PMID: 15601766 Free PMC article.

3

Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.

Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, Kamps MP, Raz E, Wagner H, Häcker G, Mann M, Karin M. Häcker H, et al. Among authors: hsu lc. Nature. 2006 Jan 12;439(7073):204-7. doi: 10.1038/nature04369. Epub 2005 Nov 23. Nature. 2006. PMID: 16306937

4

Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression.

Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Luo JL, et al. Among authors: hsu lc. Cancer Cell. 2004 Sep;6(3):297-305. doi: 10.1016/j.ccr.2004.08.012. Cancer Cell. 2004. PMID: 15380520 Free article.

5

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.

Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M. Maeda S, et al. Among authors: hsu lc. Science. 2005 Feb 4;307(5710):734-8. doi: 10.1126/science.1103685. Science. 2005. PMID: 15692052

6

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss.

Ruocco MG, Maeda S, Park JM, Lawrence T, Hsu LC, Cao Y, Schett G, Wagner EF, Karin M. Ruocco MG, et al. Among authors: hsu lc. J Exp Med. 2005 May 16;201(10):1677-87. doi: 10.1084/jem.20042081. J Exp Med. 2005. PMID: 15897281 Free PMC article.

7

A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.

Hsu LC, Ali SR, McGillivray S, Tseng PH, Mariathasan S, Humke EW, Eckmann L, Powell JJ, Nizet V, Dixit VM, Karin M. Hsu LC, et al. Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7803-8. doi: 10.1073/pnas.0802726105. Epub 2008 May 29. Proc Natl Acad Sci U S A. 2008. PMID: 18511561 Free PMC article.

8

Streptolysin O promotes group A Streptococcus immune evasion by accelerated macrophage apoptosis.

Timmer AM, Timmer JC, Pence MA, Hsu LC, Ghochani M, Frey TG, Karin M, Salvesen GS, Nizet V. Timmer AM, et al. Among authors: hsu lc. J Biol Chem. 2009 Jan 9;284(2):862-71. doi: 10.1074/jbc.M804632200. Epub 2008 Nov 11. J Biol Chem. 2009. PMID: 19001420 Free PMC article.

9

IL-1β-driven neutrophilia preserves antibacterial defense in the absence of the kinase IKKβ.

Hsu LC, Enzler T, Seita J, Timmer AM, Lee CY, Lai TY, Yu GY, Lai LC, Temkin V, Sinzig U, Aung T, Nizet V, Weissman IL, Karin M. Hsu LC, et al. Nat Immunol. 2011 Feb;12(2):144-50. doi: 10.1038/ni.1976. Epub 2010 Dec 19. Nat Immunol. 2011. PMID: 21170027 Free PMC article.

10

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta.

Greten FR, Arkan MC, Bollrath J, Hsu LC, Goode J, Miething C, Göktuna SI, Neuenhahn M, Fierer J, Paxian S, Van Rooijen N, Xu Y, O'Cain T, Jaffee BB, Busch DH, Duyster J, Schmid RM, Eckmann L, Karin M. Greten FR, et al. Among authors: hsu lc. Cell. 2007 Sep 7;130(5):918-31. doi: 10.1016/j.cell.2007.07.009. Cell. 2007. PMID: 17803913 Free PMC article.

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