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Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol.
Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW. Millson SH, et al. Among authors: hu b. FEBS J. 2007 Sep;274(17):4453-63. doi: 10.1111/j.1742-4658.2007.05974.x. Epub 2007 Aug 6. FEBS J. 2007. PMID: 17681020 Free article.
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