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The future challenges facing the development of new antimicrobial drugs.
Coates A, Hu Y, Bax R, Page C. Coates A, et al. Nat Rev Drug Discov. 2002 Nov;1(11):895-910. doi: 10.1038/nrd940. Nat Rev Drug Discov. 2002. PMID: 12415249 Review.
Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide.
Hu Y, Mangan JA, Dhillon J, Sole KM, Mitchison DA, Butcher PD, Coates AR. Hu Y, et al. J Bacteriol. 2000 Nov;182(22):6358-65. doi: 10.1128/jb.182.22.6358-6365.2000. J Bacteriol. 2000. PMID: 11053379 Free PMC article.
Novel approaches to developing new antibiotics for bacterial infections.
Coates AR, Hu Y. Coates AR, et al. Br J Pharmacol. 2007 Dec;152(8):1147-54. doi: 10.1038/sj.bjp.0707432. Epub 2007 Aug 20. Br J Pharmacol. 2007. PMID: 17704820 Free PMC article. Review.
Targeting non-multiplying organisms as a way to develop novel antimicrobials.
Coates AR, Hu Y. Coates AR, et al. Trends Pharmacol Sci. 2008 Mar;29(3):143-50. doi: 10.1016/j.tips.2007.12.001. Epub 2008 Feb 11. Trends Pharmacol Sci. 2008. PMID: 18262665 Review.
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