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Page 1
Cloning and functional analysis of two sterol-C24-methyltransferase 1 (SMT1) genes from Paris polyphylla.
Guan HY, Su P, Zhao YJ, Zhang XN, Dai ZB, Guo J, Tong YR, Liu YJ, Hu TY, Yin Y, Gao LH, Gao W, Huang LQ. Guan HY, et al. J Asian Nat Prod Res. 2018 Jul;20(7):595-604. doi: 10.1080/10286020.2016.1271791. Epub 2017 Feb 23. J Asian Nat Prod Res. 2018. PMID: 28276759
The rate-limiting enzyme S-adenosyl-L-methionine-sterol-C24-methyltransferase 1 (SMT1) facilitates the metabolic flux toward phytosterols. It catalyzes the methylation of the cycloartenol in the side chain of the C24-alkyl group, to generate 24(28)-methylene cycloartenol. …
The rate-limiting enzyme S-adenosyl-L-methionine-sterol-C24-methyltransferase 1 (SMT1) facilitates the metabolic flux toward phytoste …
A new N-methoxyl-carbonyl benzylisoquinoline from Litsea cubeba.
Tang B, Tu H, Long HA, Du J, Guo JM, Liu HJ, Hu X, Yang L, Du X. Tang B, et al. J Asian Nat Prod Res. 2017 Sep;19(9):941-945. doi: 10.1080/10286020.2016.1275582. Epub 2017 Feb 2. J Asian Nat Prod Res. 2017. PMID: 28152615
A new benzylisoquinoline alkaloid ( )-N-methoxycarbonyl-norjuziphine (1) was isolated from Litsea cubeba. Its structure was identified by extensively spectroscopic techniques and confirmed by the single-crystal X-ray diffraction analysis. Compound 1 showed cytotoxic …
A new benzylisoquinoline alkaloid ( )-N-methoxycarbonyl-norjuziphine (1) was isolated from Litsea cubeba. Its structure was identifie …
A new steroidal saponin from Polygonatum sibiricum.
Zhang HY, Hu WC, Ma GX, Zhu NL, Sun XB, Wu HF, Xu XD. Zhang HY, et al. J Asian Nat Prod Res. 2018 Jun;20(6):586-592. doi: 10.1080/10286020.2017.1351436. Epub 2017 Nov 23. J Asian Nat Prod Res. 2018. PMID: 29168389
A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic extract of Polygonatum sibiricum Delar. ex Redoute. ...Compounds 3-5 showed significant cytotoxicity against HepG2 cell lines with IC(50) value …
A new furostan type steroidal saponin, kingianoside Z (1), along with four known compounds (2-5), was isolated from the ethanolic ext …
Ergostane steroids from the ethanol extract of Dysoxylum mollissimum.
Huang XY, Liu ZM, Shi HP, Hu J, Han DX. Huang XY, et al. J Asian Nat Prod Res. 2019 Feb;21(2):103-108. doi: 10.1080/10286020.2017.1392513. Epub 2017 Oct 30. J Asian Nat Prod Res. 2019. PMID: 29082753
Structural elucidation of all the compounds was performed by spectral methods such as 1D and 2D ((1)H-(1)H COSY, HMQC, and HMBC) NMR spectroscopy, in addition to high resolution mass spectrometry. All the isolated steroids were in vitro evaluated for their anti-infl …
Structural elucidation of all the compounds was performed by spectral methods such as 1D and 2D ((1)H-(1)H COSY, HMQC, and HMB …
New bioactive compounds from aquatic endophyte Chaetomium globosum.
Ruan BH, Yu ZF, Yang XQ, Yang YB, Hu M, Zhang ZX, Zhou QY, Zhou H, Ding ZT. Ruan BH, et al. Nat Prod Res. 2018 May;32(9):1050-1055. doi: 10.1080/14786419.2017.1378210. Epub 2017 Sep 19. Nat Prod Res. 2018. PMID: 28927295
Two new oxidation products-related aureonitol and cytochalasan were isolated from Chaetomium globosum fermented in Chinese yam (Dioscorea opposita) and determined as 10,11-dihydroxyl- aureonitol (1) and yamchaetoglobosin A (2). Compound 2 indicated significant inhibitory e …
Two new oxidation products-related aureonitol and cytochalasan were isolated from Chaetomium globosum fermented in Chinese yam (Dioscorea op …
Monoterpenoid indole alkaloids from Alstonia mairei and their cytotoxicity.
Yan TL, Han DX, Hu J, Huang XY, Wang HK. Yan TL, et al. J Asian Nat Prod Res. 2017 Jun;19(6):550-556. doi: 10.1080/10286020.2017.1313242. Epub 2017 Apr 9. J Asian Nat Prod Res. 2017. PMID: 28393571
Phytochemical investigation on the 70% ethanol extract of the leaves of Alstonia mairei resulted in the isolation of three new monoterpenoid indole alkaloids, alstomairines A-C (1-3), along with one known compound, alpneumine A (4). Structural elucidation of all the compou …
Phytochemical investigation on the 70% ethanol extract of the leaves of Alstonia mairei resulted in the isolation of three new monoterpenoid …
Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.
Hu X, Yu MH, Yan GR, Wang HY, Hou AJ, Lei C. Hu X, et al. J Asian Nat Prod Res. 2018 May;20(5):488-493. doi: 10.1080/10286020.2017.1350653. Epub 2017 Nov 30. J Asian Nat Prod Res. 2018. PMID: 29191050
A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. ...
A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder addu …
Antiviral activity of aconite alkaloids from Aconitum carmichaelii Debx.
Xu W, Zhang M, Liu H, Wei K, He M, Li X, Hu D, Yang S, Zheng Y. Xu W, et al. Nat Prod Res. 2019 May;33(10):1486-1490. doi: 10.1080/14786419.2017.1416385. Epub 2017 Dec 22. Nat Prod Res. 2019. PMID: 29271255
By contrast, compound c presented inactivation activity of 52.1% against CMV at 500 mug/mL, which was almost equal to that of the commercial Ningnanmycin (87.1% inactivation activity against TMV and 53.8% inactivation activity against CMV). ...
By contrast, compound c presented inactivation activity of 52.1% against CMV at 500 mug/mL, which was almost equal to that of the com …
Two new biphenyls from the stems of Garcinia tetralata.
Ji BK, Gao XM, Cui D, Wang SS, Huang WZ, Li YK, Mei SX, Yang Z, Li GP, Jiang MY, He YH, Jiang ZY, Du G, Pan XX, Liu WX, Hu QF. Ji BK, et al. Nat Prod Res. 2017 Jul;31(13):1544-1550. doi: 10.1080/14786419.2017.1283492. Epub 2017 Feb 5. Nat Prod Res. 2017. PMID: 28161987
Two new biphenyls (1 and 2) and three known xanthones (3-5) were isolated from the ethanol extract of the stems of Garcinia tetralata. ...Compounds 1-2 showed anti-rotavirus activities with SI above 10....
Two new biphenyls (1 and 2) and three known xanthones (3-5) were isolated from the ethanol extract of the stems of Garcinia tetralata …
Two new geranylphenylacetate glycosides from the barks of Cinnamomum cassia.
Zeng JF, Zhu HC, Lu JW, Hu LZ, Song JC, Zhang YH. Zeng JF, et al. Nat Prod Res. 2017 Aug;31(15):1812-1818. doi: 10.1080/14786419.2017.1294175. Epub 2017 Mar 6. Nat Prod Res. 2017. PMID: 28278616
Two new glycosides, cinnacassides F (1) and G (2), with a rare geranylphenylacetate carbon skeleton, were isolated from the barks of Cinnamomum cassia, along with three known analogues, cinnacassides A (3), B (4) and C (5). The structures of the new compounds were elucidat …
Two new glycosides, cinnacassides F (1) and G (2), with a rare geranylphenylacetate carbon skeleton, were isolated from the barks of …
34 results