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Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.
Sbidian E, Chaimani A, Guelimi R, Garcia-Doval I, Hua C, Hughes C, Naldi L, Kinberger M, Afach S, Le Cleach L. Sbidian E, et al. Cochrane Database Syst Rev. 2023 Jul 12;7(7):CD011535. doi: 10.1002/14651858.CD011535.pub6. Cochrane Database Syst Rev. 2023. PMID: 37436070 Free PMC article. Review.
Network meta-analysis at class level showed that all interventions (non-biological systemic agents, small molecules, and biological treatments) showed a higher proportion of patients reaching PASI 90 than placebo. ...For reaching PASI 90, the most effective drugs when comp …
Network meta-analysis at class level showed that all interventions (non-biological systemic agents, small molecules, and biological t …
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.
Sbidian E, Chaimani A, Garcia-Doval I, Doney L, Dressler C, Hua C, Hughes C, Naldi L, Afach S, Le Cleach L. Sbidian E, et al. Cochrane Database Syst Rev. 2022 May 23;5(5):CD011535. doi: 10.1002/14651858.CD011535.pub5. Cochrane Database Syst Rev. 2022. Update in: Cochrane Database Syst Rev. 2023 Jul 12;7:CD011535. doi: 10.1002/14651858.CD011535.pub6. PMID: 35603936 Free PMC article. Updated.
OBJECTIVES: To compare the efficacy and safety of non-biological systemic agents, small molecules, and biologics for people with moderate-to-severe psoriasis using a network meta-analysis, and to provide a ranking of these treatments according to their efficacy and safety. …
OBJECTIVES: To compare the efficacy and safety of non-biological systemic agents, small molecules, and biologics for people with mode …
Microfluidic Microalgae System: A Review.
Alias AB, Mishra S, Pendharkar G, Chen CS, Liu CH, Liu YJ, Yao DJ. Alias AB, et al. Molecules. 2022 Mar 15;27(6):1910. doi: 10.3390/molecules27061910. Molecules. 2022. PMID: 35335274 Free PMC article. Review.
Applications of Single-Molecule Vibrational Spectroscopic Techniques for the Structural Investigation of Amyloid Oligomers.
Vu KHP, Blankenburg GH, Lesser-Rojas L, Chou CF. Vu KHP, et al. Molecules. 2022 Sep 30;27(19):6448. doi: 10.3390/molecules27196448. Molecules. 2022. PMID: 36234985 Free PMC article. Review.
However, structural investigations are challenging due to the low abundance and heterogeneity of those metastable intermediate species. Single-molecule techniques have the potential to overcome these difficulties. This review aims to report some of the recent advances and …
However, structural investigations are challenging due to the low abundance and heterogeneity of those metastable intermediate species. Sing …
Fluorescent and Phosphorescent Nitrogen-Containing Heterocycles and Crown Ethers: Biological and Pharmaceutical Applications.
Ullah F, Ullah S, Khan MFA, Mustaqeem M, Paracha RN, Rehman MFU, Kanwal F, Hassan SSU, Bungau S. Ullah F, et al. Molecules. 2022 Oct 6;27(19):6631. doi: 10.3390/molecules27196631. Molecules. 2022. PMID: 36235167 Free PMC article. Review.
Fluorescent molecules absorb photons of specific wavelengths and emit a longer wavelength photon within nanoseconds. ...
Fluorescent molecules absorb photons of specific wavelengths and emit a longer wavelength photon within nanoseconds. ...
Polygonum capitatum, the Hmong Medicinal Flora: A Comprehensive Review of Its Phytochemical, Pharmacological and Pharmacokinetic Characteristics.
Lin Y, He L, Chen XJ, Zhang X, Yan XL, Tu B, Zeng Z, He MH. Lin Y, et al. Molecules. 2022 Sep 28;27(19):6407. doi: 10.3390/molecules27196407. Molecules. 2022. PMID: 36234943 Free PMC article. Review.
Polygonum capitatum, known as "Tou Hua Liao" (Chinese name), is a crucial source of Hmong medicinal plants that has benefited human health for a long time. ...The purpose of this paper was to provide a systematic and comprehensive overview of the traditional usages, botany …
Polygonum capitatum, known as "Tou Hua Liao" (Chinese name), is a crucial source of Hmong medicinal plants that has benefited human h …
Discovery of a Novel Oral Proteasome Inhibitor to Block NLRP3 Inflammasome Activation with Anti-inflammation Activity.
Wu X, Sun P, Chen X, Hua L, Cai H, Liu Z, Zhang C, Liang S, Chen Y, Wu D, Ou Y, Hu W, Yang Z. Wu X, et al. J Med Chem. 2022 Sep 22;65(18):11985-12001. doi: 10.1021/acs.jmedchem.2c00523. Epub 2022 Sep 5. J Med Chem. 2022. PMID: 36063115
NLRP3 inflammasome activation plays a critical role in inflammation-related disorders. More small-molecule entities are needed to study the mechanism of NLRP3 inflammasome activation and to validate the efficacy and safety of the NLRP3 pathway. Herein, we report the discov …
NLRP3 inflammasome activation plays a critical role in inflammation-related disorders. More small-molecule entities are needed to stu …
41 results