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CYP2B6 polymorphisms influence the plasma concentration and clearance of the methadone S-enantiomer.
Wang SC, Ho IK, Tsou HH, Tian JN, Hsiao CF, Chen CH, Tan HK, Lin L, Wu CS, Su LW, Huang CL, Yang YH, Liu ML, Lin KM, Chen CY, Liu SC, Wu HY, Chan HW, Tsai MH, Lin PS, Liu YL. Wang SC, et al. Among authors: huang cl. J Clin Psychopharmacol. 2011 Aug;31(4):463-9. doi: 10.1097/JCP.0b013e318222b5dd. J Clin Psychopharmacol. 2011. PMID: 21694616 Clinical Trial.
Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.
Wang SC, Tsou HH, Chen CH, Chen YT, Ho IK, Hsiao CF, Chou SY, Lin YF, Fang KC, Huang CL, Su LW, Fang YC, Liu ML, Wu HY, Lin KM, Liu SC, Kuo HW, Chiang IC, Chen AC, Tian JN, Liu YL. Wang SC, et al. Among authors: huang cl. Eur Neuropsychopharmacol. 2012 Oct;22(10):695-703. doi: 10.1016/j.euroneuro.2012.02.002. Epub 2012 Mar 9. Eur Neuropsychopharmacol. 2012. PMID: 22406240 Clinical Trial.
PXR polymorphisms interacted with CYP2B6 polymorphisms on methadone metabolites.
Tsai HJ, Wang SC, Tian JN, Chang TK, Ho IK, Hsiao CF, Chen CH, Tan HK, Lin L, Wu CS, Su LW, Huang CL, Yang YH, Liu ML, Lin KM, Liu YL. Tsai HJ, et al. Among authors: huang cl. J Clin Psychopharmacol. 2013 Feb;33(1):137-40. doi: 10.1097/01.jcp.0000426186.34421.de. J Clin Psychopharmacol. 2013. PMID: 23288240 No abstract available.
Functional genetic polymorphisms in CYP2C19 gene in relation to cardiac side effects and treatment dose in a methadone maintenance cohort.
Wang SC, Ho IK, Tsou HH, Liu SW, Hsiao CF, Chen CH, Tan HK, Lin L, Wu CS, Su LW, Huang CL, Yang YH, Liu ML, Lin KM, Liu SC, Wu HY, Kuo HW, Chen AC, Chang YS, Liu YL. Wang SC, et al. Among authors: huang cl. OMICS. 2013 Oct;17(10):519-26. doi: 10.1089/omi.2012.0068. Epub 2013 Sep 9. OMICS. 2013. PMID: 24016178 Free PMC article.
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.
Yang HC, Chu SK, Huang CL, Kuo HW, Wang SC, Liu SW, Ho IK, Liu YL. Yang HC, et al. Among authors: huang cl. PLoS Genet. 2016 Mar 24;12(3):e1005910. doi: 10.1371/journal.pgen.1005910. eCollection 2016 Mar. PLoS Genet. 2016. PMID: 27010727 Free PMC article.
1,564 results