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Improving fascin inhibitors to block tumor cell migration and metastasis.
Han S, Huang J, Liu B, Xing B, Bordeleau F, Reinhart-King CA, Li W, Zhang JJ, Huang XY. Han S, et al. Among authors: huang xy, huang j. Mol Oncol. 2016 Aug;10(7):966-80. doi: 10.1016/j.molonc.2016.03.006. Epub 2016 Apr 1. Mol Oncol. 2016. PMID: 27071719 Free PMC article.
Molecular mechanism of fascin function in filopodial formation.
Yang S, Huang FK, Huang J, Chen S, Jakoncic J, Leo-Macias A, Diaz-Avalos R, Chen L, Zhang JJ, Huang XY. Yang S, et al. Among authors: huang xy, huang fk, huang j. J Biol Chem. 2013 Jan 4;288(1):274-84. doi: 10.1074/jbc.M112.427971. Epub 2012 Nov 26. J Biol Chem. 2013. PMID: 23184945 Free PMC article.
A signal transducer and activator of transcription 3·Nuclear Factor κB (Stat3·NFκB) complex is necessary for the expression of fascin in metastatic breast cancer cells in response to interleukin (IL)-6 and tumor necrosis factor (TNF)-α.
Snyder M, Huang J, Huang XY, Zhang JJ. Snyder M, et al. Among authors: huang xy, huang j. J Biol Chem. 2014 Oct 24;289(43):30082-9. doi: 10.1074/jbc.M114.591719. Epub 2014 Sep 11. J Biol Chem. 2014. PMID: 25213863 Free PMC article.
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