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Acute stress results in skin corticotropin-releasing hormone secretion, mast cell activation and vascular permeability, an effect mimicked by intradermal corticotropin-releasing hormone and inhibited by histamine-1 receptor antagonists.
Lytinas M, Kempuraj D, Huang M, Boucher W, Esposito P, Theoharides TC. Lytinas M, et al. Among authors: huang m. Int Arch Allergy Immunol. 2003 Mar;130(3):224-31. doi: 10.1159/000069516. Int Arch Allergy Immunol. 2003. PMID: 12660427
Azelastine's inhibition of histamine and tryptase release from human umbilical cord blood-derived cultured mast cells as well as rat skin mast cell-induced vascular permeability: comparison with olopatadine.
Lytinas M, Kempuraj D, Huang M, Kandere K, Boucher W, Letourneau R, Jeudy S, Fitzgerald K, Spear K, Athanasiou A, Theoharides TC. Lytinas M, et al. Among authors: huang m. Allergy Asthma Proc. 2002 Jan-Feb;23(1):45-51. Allergy Asthma Proc. 2002. PMID: 11894734
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