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6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.
Buckley BJ, Aboelela A, Minaei E, Jiang LX, Xu Z, Ali U, Fildes K, Cheung CY, Cook SM, Johnson DC, Bachovchin DA, Cook GM, Apte M, Huang M, Ranson M, Kelso MJ. Buckley BJ, et al. Among authors: huang m. J Med Chem. 2018 Sep 27;61(18):8299-8320. doi: 10.1021/acs.jmedchem.8b00838. Epub 2018 Sep 7. J Med Chem. 2018. PMID: 30130401 Free PMC article.
Structural basis for therapeutic intervention of uPA/uPAR system.
Ngo JC, Jiang L, Lin Z, Yuan C, Chen Z, Zhang X, Yu H, Wang J, Lin L, Huang M. Ngo JC, et al. Among authors: huang m. Curr Drug Targets. 2011 Nov;12(12):1729-43. doi: 10.2174/138945011797635911. Curr Drug Targets. 2011. PMID: 21707478 Review.
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