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Accurate de novo design of hyperstable constrained peptides.
Bhardwaj G, Mulligan VK, Bahl CD, Gilmore JM, Harvey PJ, Cheneval O, Buchko GW, Pulavarti SV, Kaas Q, Eletsky A, Huang PS, Johnsen WA, Greisen PJ, Rocklin GJ, Song Y, Linsky TW, Watkins A, Rettie SA, Xu X, Carter LP, Bonneau R, Olson JM, Coutsias E, Correnti CE, Szyperski T, Craik DJ, Baker D. Bhardwaj G, et al. Among authors: huang ps. Nature. 2016 Oct 20;538(7625):329-335. doi: 10.1038/nature19791. Epub 2016 Sep 14. Nature. 2016. PMID: 27626386 Free PMC article.
A general computational approach for repeat protein design.
Parmeggiani F, Huang PS, Vorobiev S, Xiao R, Park K, Caprari S, Su M, Seetharaman J, Mao L, Janjua H, Montelione GT, Hunt J, Baker D. Parmeggiani F, et al. Among authors: huang ps. J Mol Biol. 2015 Jan 30;427(2):563-75. doi: 10.1016/j.jmb.2014.11.005. Epub 2014 Nov 14. J Mol Biol. 2015. PMID: 25451037 Free PMC article.
Control of repeat-protein curvature by computational protein design.
Park K, Shen BW, Parmeggiani F, Huang PS, Stoddard BL, Baker D. Park K, et al. Among authors: huang ps. Nat Struct Mol Biol. 2015 Feb;22(2):167-74. doi: 10.1038/nsmb.2938. Epub 2015 Jan 12. Nat Struct Mol Biol. 2015. PMID: 25580576 Free PMC article.
Exploring the repeat protein universe through computational protein design.
Brunette TJ, Parmeggiani F, Huang PS, Bhabha G, Ekiert DC, Tsutakawa SE, Hura GL, Tainer JA, Baker D. Brunette TJ, et al. Among authors: huang ps. Nature. 2015 Dec 24;528(7583):580-4. doi: 10.1038/nature16162. Epub 2015 Dec 16. Nature. 2015. PMID: 26675729 Free PMC article.
Design of a hyperstable 60-subunit protein dodecahedron. [corrected].
Hsia Y, Bale JB, Gonen S, Shi D, Sheffler W, Fong KK, Nattermann U, Xu C, Huang PS, Ravichandran R, Yi S, Davis TN, Gonen T, King NP, Baker D. Hsia Y, et al. Among authors: huang ps. Nature. 2016 Jul 7;535(7610):136-9. doi: 10.1038/nature18010. Epub 2016 Jun 15. Nature. 2016. PMID: 27309817 Free PMC article.
236 results