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The thyroid hormone-inactivating deiodinase functions as a homodimer.
Sagar GD, Gereben B, Callebaut I, Mornon JP, Zeöld A, Curcio-Morelli C, Harney JW, Luongo C, Mulcahey MA, Larsen PR, Huang SA, Bianco AC. Sagar GD, et al. Among authors: huang sa. Mol Endocrinol. 2008 Jun;22(6):1382-93. doi: 10.1210/me.2007-0490. Epub 2008 Mar 20. Mol Endocrinol. 2008. PMID: 18356288 Free PMC article.
Knockdown of the type 3 iodothyronine deiodinase (D3) interacting protein peroxiredoxin 3 decreases D3-mediated deiodination in intact cells.
Aerts G, Arrojo E Drigo R, Van Herck SL, Sammels E, Mirebeau-Prunier D, Gereben B, Zeöld A, Harney JW, Huang SA, Mulcahey MA, Van der Geyten S, Van den Bergh G, Arckens L, Darras VM, Zavacki AM. Aerts G, et al. Among authors: huang sa. Endocrinology. 2009 Nov;150(11):5171-80. doi: 10.1210/en.2009-0702. Epub 2009 Oct 9. Endocrinology. 2009. PMID: 19819956 Free PMC article.
Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.
Dentice M, Luongo C, Huang S, Ambrosio R, Elefante A, Mirebeau-Prunier D, Zavacki AM, Fenzi G, Grachtchouk M, Hutchin M, Dlugosz AA, Bianco AC, Missero C, Larsen PR, Salvatore D. Dentice M, et al. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14466-71. doi: 10.1073/pnas.0706754104. Epub 2007 Aug 24. Proc Natl Acad Sci U S A. 2007. PMID: 17720805 Free PMC article.
154 results