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Evaluation of various static in vitro-in vivo extrapolation models for risk assessment of the CYP3A inhibition potential of an investigational drug.
Vieira ML, Kirby B, Ragueneau-Majlessi I, Galetin A, Chien JY, Einolf HJ, Fahmi OA, Fischer V, Fretland A, Grime K, Hall SD, Higgs R, Plowchalk D, Riley R, Seibert E, Skordos K, Snoeys J, Venkatakrishnan K, Waterhouse T, Obach RS, Berglund EG, Zhang L, Zhao P, Reynolds KS, Huang SM. Vieira ML, et al. Among authors: huang sm. Clin Pharmacol Ther. 2014 Feb;95(2):189-98. doi: 10.1038/clpt.2013.187. Epub 2013 Sep 18. Clin Pharmacol Ther. 2014. PMID: 24048277
Transporter-mediated drug-drug interactions.
Zhang L, Huang SM, Lesko LJ. Zhang L, et al. Among authors: huang sm. Clin Pharmacol Ther. 2011 Apr;89(4):481-4. doi: 10.1038/clpt.2010.359. Clin Pharmacol Ther. 2011. PMID: 21423238
Cancer Therapy: Shooting for the Moon.
Lee J, Blumenthal GM, Hohl RJ, Huang SM. Lee J, et al. Among authors: huang sm. Clin Pharmacol Ther. 2017 May;101(5):552-558. doi: 10.1002/cpt.655. Clin Pharmacol Ther. 2017. PMID: 28418166 Free PMC article. No abstract available.
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