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1,032 results
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Evaluation of various static in vitro-in vivo extrapolation models for risk assessment of the CYP3A inhibition potential of an investigational drug.
Vieira ML, Kirby B, Ragueneau-Majlessi I, Galetin A, Chien JY, Einolf HJ, Fahmi OA, Fischer V, Fretland A, Grime K, Hall SD, Higgs R, Plowchalk D, Riley R, Seibert E, Skordos K, Snoeys J, Venkatakrishnan K, Waterhouse T, Obach RS, Berglund EG, Zhang L, Zhao P, Reynolds KS, Huang SM. Vieira ML, et al. Among authors: huang sm. Clin Pharmacol Ther. 2014 Feb;95(2):189-98. doi: 10.1038/clpt.2013.187. Epub 2013 Sep 18. Clin Pharmacol Ther. 2014. PMID: 24048277
Confidence in generic drug substitution.
Lionberger R, Jiang W, Huang SM, Geba G. Lionberger R, et al. Among authors: huang sm. Clin Pharmacol Ther. 2013 Oct;94(4):438-40. doi: 10.1038/clpt.2013.104. Clin Pharmacol Ther. 2013. PMID: 24048239
Transporter-mediated drug-drug interactions.
Zhang L, Huang SM, Lesko LJ. Zhang L, et al. Among authors: huang sm. Clin Pharmacol Ther. 2011 Apr;89(4):481-4. doi: 10.1038/clpt.2010.359. Clin Pharmacol Ther. 2011. PMID: 21423238
Organ Impairment-Drug-Drug Interaction Database: A Tool for Evaluating the Impact of Renal or Hepatic Impairment and Pharmacologic Inhibition on the Systemic Exposure of Drugs.
Yeung CK, Yoshida K, Kusama M, Zhang H, Ragueneau-Majlessi I, Argon S, Li L, Chang P, Le CD, Zhao P, Zhang L, Sugiyama Y, Huang SM. Yeung CK, et al. Among authors: huang sm. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):489-94. doi: 10.1002/psp4.55. Epub 2015 Jul 14. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26380158 Free PMC article.
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