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The epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammation in an asthma model.
Nakagami Y, Favoreto S Jr, Zhen G, Park SW, Nguyenvu LT, Kuperman DA, Dolganov GM, Huang X, Boushey HA, Avila PC, Erle DJ. Nakagami Y, et al. Among authors: huang x. J Immunol. 2008 Aug 1;181(3):2203-10. doi: 10.4049/jimmunol.181.3.2203. J Immunol. 2008. PMID: 18641360 Free PMC article.
Distinct roles of FOXA2 and FOXA3 in allergic airway disease and asthma.
Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff PG, Fahy JV, Erle DJ. Park SW, et al. Among authors: huang x. Am J Respir Crit Care Med. 2009 Oct 1;180(7):603-10. doi: 10.1164/rccm.200811-1768OC. Epub 2009 Jul 23. Am J Respir Crit Care Med. 2009. PMID: 19628779 Free PMC article.
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