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2,681 results
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Unperturbed islet α-cell function examined in mouse pancreas tissue slices.
Huang YC, Rupnik M, Gaisano HY. Huang YC, et al. J Physiol. 2011 Jan 15;589(Pt 2):395-408. doi: 10.1113/jphysiol.2010.200345. Epub 2010 Nov 15. J Physiol. 2011. PMID: 21078586 Free PMC article.
Munc18c mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose stimulated insulin secretion in human pancreatic beta-cells.
Zhu D, Xie L, Karimian N, Liang T, Kang Y, Huang YC, Gaisano HY. Zhu D, et al. Among authors: huang yc. Mol Metab. 2015 Feb 16;4(5):418-26. doi: 10.1016/j.molmet.2015.02.004. eCollection 2015 May. Mol Metab. 2015. PMID: 25973389 Free PMC article.
Ex vivo human pancreatic slice preparations offer a valuable model for studying pancreatic exocrine biology.
Liang T, Dolai S, Xie L, Winter E, Orabi AI, Karimian N, Cosen-Binker LI, Huang YC, Thorn P, Cattral MS, Gaisano HY. Liang T, et al. Among authors: huang yc. J Biol Chem. 2017 Apr 7;292(14):5957-5969. doi: 10.1074/jbc.M117.777433. Epub 2017 Feb 27. J Biol Chem. 2017. PMID: 28242761 Free PMC article.
Syntaxin-4 mediates exocytosis of pre-docked and newcomer insulin granules underlying biphasic glucose-stimulated insulin secretion in human pancreatic beta cells.
Xie L, Zhu D, Dolai S, Liang T, Qin T, Kang Y, Xie H, Huang YC, Gaisano HY. Xie L, et al. Among authors: huang yc. Diabetologia. 2015 Jun;58(6):1250-9. doi: 10.1007/s00125-015-3545-4. Epub 2015 Mar 13. Diabetologia. 2015. PMID: 25762204
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.
Huang YC, Rupnik MS, Karimian N, Herrera PL, Gilon P, Feng ZP, Gaisano HY. Huang YC, et al. Diabetes. 2013 Feb;62(2):519-30. doi: 10.2337/db11-0786. Epub 2012 Oct 5. Diabetes. 2013. PMID: 23043159 Free PMC article.
Electrophysiological identification of mouse islet α-cells: from isolated single α-cells to in situ assessment within pancreas slices.
Huang YC, Gaisano HY, Leung YM. Huang YC, et al. Islets. 2011 Jul-Aug;3(4):139-43. doi: 10.4161/isl.3.4.16166. Epub 2011 Jul 1. Islets. 2011. PMID: 21623173 Review.
Botulinum neurotoxin A and neurotoxin E cleavage products of synaptosome-associated protein of 25 kd exhibit distinct actions on pancreatic islet beta-cell Kv2.1 channel gating.
He Y, Elias CL, Huang YC, Gao X, Leung YM, Kang Y, Xie H, Chaddock JA, Tsushima RG, Gaisano HY. He Y, et al. Among authors: huang yc. Pancreas. 2008 Jan;36(1):10-7. doi: 10.1097/mpa.0b013e31812eee28. Pancreas. 2008. PMID: 18192874
Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced beta-cell excitability via activation of adenosine 5'-triphosphate-sensitive potassium channels.
Webster NJ, Searle GJ, Lam PP, Huang YC, Riedel MJ, Harb G, Gaisano HY, Holt A, Light PE. Webster NJ, et al. Among authors: huang yc. Endocrinology. 2008 Jul;149(7):3679-87. doi: 10.1210/en.2007-1138. Epub 2008 Mar 27. Endocrinology. 2008. PMID: 18372336
Somatostatin receptor type 2 antagonism improves glucagon counterregulation in biobreeding diabetic rats.
Karimian N, Qin T, Liang T, Osundiji M, Huang Y, Teich T, Riddell MC, Cattral MS, Coy DH, Vranic M, Gaisano HY. Karimian N, et al. Diabetes. 2013 Aug;62(8):2968-77. doi: 10.2337/db13-0164. Epub 2013 Apr 29. Diabetes. 2013. PMID: 23630299 Free PMC article.
POU homeodomain protein Oct-1 functions as a sensor for cyclic AMP.
Wang P, Wang Q, Sun J, Wu J, Li H, Zhang N, Huang Y, Su B, Li RK, Liu L, Zhang Y, Elsholtz HP, Hu J, Gaisano HY, Jin T. Wang P, et al. J Biol Chem. 2009 Sep 25;284(39):26456-65. doi: 10.1074/jbc.M109.030668. Epub 2009 Jul 18. J Biol Chem. 2009. PMID: 19617623 Free PMC article.
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