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Programmable co-delivery of the immune checkpoint inhibitor NLG919 and chemotherapeutic doxorubicin via a redox-responsive immunostimulatory polymeric prodrug carrier.
Sun JJ, Chen YC, Huang YX, Zhao WC, Liu YH, Venkataramanan R, Lu BF, Li S. Sun JJ, et al. Acta Pharmacol Sin. 2017 Jun;38(6):823-834. doi: 10.1038/aps.2017.44. Epub 2017 May 8. Acta Pharmacol Sin. 2017. PMID: 28504251 Free PMC article.
A prodrug micellar carrier assembled from polymers with pendant farnesyl thiosalicylic acid moieties for improved delivery of paclitaxel.
Sun J, Chen Y, Li K, Huang Y, Fu X, Zhang X, Zhao W, Wei Y, Xu L, Zhang P, Venkataramanan R, Li S. Sun J, et al. Acta Biomater. 2016 Oct 1;43:282-291. doi: 10.1016/j.actbio.2016.07.014. Epub 2016 Jul 12. Acta Biomater. 2016. PMID: 27422196 Free PMC article.
Effective co-delivery of doxorubicin and dasatinib using a PEG-Fmoc nanocarrier for combination cancer chemotherapy.
Zhang P, Li J, Ghazwani M, Zhao W, Huang Y, Zhang X, Venkataramanan R, Li S. Zhang P, et al. Biomaterials. 2015 Oct;67:104-14. doi: 10.1016/j.biomaterials.2015.07.027. Epub 2015 Jul 15. Biomaterials. 2015. PMID: 26210177 Free PMC article.
Metabolism of KO143, an ABCG2 inhibitor.
Liu K, Zhu J, Huang Y, Li C, Lu J, Sachar M, Li S, Ma X. Liu K, et al. Drug Metab Pharmacokinet. 2017 Aug;32(4):193-200. doi: 10.1016/j.dmpk.2017.02.003. Epub 2017 Mar 6. Drug Metab Pharmacokinet. 2017. PMID: 28619281
Regulation of hepatic stellate cell proliferation and activation by glutamine metabolism.
Li J, Ghazwani M, Liu K, Huang Y, Chang N, Fan J, He F, Li L, Bu S, Xie W, Ma X, Li S. Li J, et al. PLoS One. 2017 Aug 10;12(8):e0182679. doi: 10.1371/journal.pone.0182679. eCollection 2017. PLoS One. 2017. PMID: 28797105 Free PMC article.
Novel glucosylceramide synthase inhibitor based prodrug copolymer micelles for delivery of anticancer agents.
Xu J, Zhao W, Sun J, Huang Y, Wang P, Venkataramanan R, Yang D, Ma X, Rana A, Li S. Xu J, et al. J Control Release. 2018 Oct 28;288:212-226. doi: 10.1016/j.jconrel.2018.09.011. Epub 2018 Sep 14. J Control Release. 2018. PMID: 30223045 Free PMC article.
A Nanomicellar Prodrug Carrier Based on Ibuprofen-Conjugated Polymer for Co-delivery of Doxorubicin.
Li Z, Sun J, Huang Y, Liu Y, Xu J, Chen Y, Liang L, Li J, Liao Q, Li S, Zhou K. Li Z, et al. Front Pharmacol. 2018 Aug 14;9:781. doi: 10.3389/fphar.2018.00781. eCollection 2018. Front Pharmacol. 2018. PMID: 30154714 Free PMC article.
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