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Normal alveolar epithelial lining fluid contains high levels of glutathione.
Cantin AM, North SL, Hubbard RC, Crystal RG. Cantin AM, et al. J Appl Physiol (1985). 1987 Jul;63(1):152-7. doi: 10.1152/jappl.1987.63.1.152. J Appl Physiol (1985). 1987. PMID: 3040659
Augmentation of lung antineutrophil elastase capacity with recombinant human alpha-1-antitrypsin.
Casolaro MA, Fells G, Wewers M, Pierce JE, Ogushi F, Hubbard R, Sellers S, Forstrom J, Lyons D, Kawasaki G, et al. Casolaro MA, et al. J Appl Physiol (1985). 1987 Nov;63(5):2015-23. doi: 10.1152/jappl.1987.63.5.2015. J Appl Physiol (1985). 1987. PMID: 3500941
Recombinant secretory leukoprotease inhibitor augments glutathione levels in lung epithelial lining fluid.
Gillissen A, Birrer P, McElvaney NG, Buhl R, Vogelmeier C, Hoyt RF Jr, Hubbard RC, Crystal RG. Gillissen A, et al. J Appl Physiol (1985). 1993 Aug;75(2):825-32. doi: 10.1152/jappl.1993.75.2.825. J Appl Physiol (1985). 1993. PMID: 7901193
Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.
Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG. Cantin AM, et al. J Clin Invest. 1987 Jun;79(6):1665-73. doi: 10.1172/JCI113005. J Clin Invest. 1987. PMID: 3034979 Free PMC article.
Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol.
Buhl R, Vogelmeier C, Critenden M, Hubbard RC, Hoyt RF Jr, Wilson EM, Cantin AM, Crystal RG. Buhl R, et al. Proc Natl Acad Sci U S A. 1990 Jun;87(11):4063-7. doi: 10.1073/pnas.87.11.4063. Proc Natl Acad Sci U S A. 1990. PMID: 2349219 Free PMC article.
Aerosolization of recombinant SLPI to augment antineutrophil elastase protection of pulmonary epithelium.
Vogelmeier C, Buhl R, Hoyt RF, Wilson E, Fells GA, Hubbard RC, Schnebli HP, Thompson RC, Crystal RG. Vogelmeier C, et al. J Appl Physiol (1985). 1990 Nov;69(5):1843-8. doi: 10.1152/jappl.1990.69.5.1843. J Appl Physiol (1985). 1990. PMID: 2272977
Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis.
Borok Z, Buhl R, Grimes GJ, Bokser AD, Hubbard RC, Holroyd KJ, Roum JH, Czerski DB, Cantin AM, Crystal RG. Borok Z, et al. Lancet. 1991 Jul 27;338(8761):215-6. doi: 10.1016/0140-6736(91)90350-x. Lancet. 1991. PMID: 1676780
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