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The highly efficacious actions of N-desmethylclozapine at muscarinic receptors are unique and not a common property of either typical or atypical antipsychotic drugs: is M1 agonism a pre-requisite for mimicking clozapine's actions?
Davies MA, Compton-Toth BA, Hufeisen SJ, Meltzer HY, Roth BL. Davies MA, et al. Among authors: hufeisen sj. Psychopharmacology (Berl). 2005 Apr;178(4):451-60. doi: 10.1007/s00213-004-2017-1. Epub 2004 Oct 13. Psychopharmacology (Berl). 2005. PMID: 15765260
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