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12 results
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Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis.
Kajiya K, Sawane M, Huggenberger R, Detmar M. Kajiya K, et al. Among authors: huggenberger r. J Invest Dermatol. 2009 May;129(5):1292-8. doi: 10.1038/jid.2008.351. Epub 2008 Nov 13. J Invest Dermatol. 2009. PMID: 19005491 Free article.
Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.
Schonthaler HB, Huggenberger R, Wculek SK, Detmar M, Wagner EF. Schonthaler HB, et al. Among authors: huggenberger r. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21264-9. doi: 10.1073/pnas.0907550106. Epub 2009 Dec 7. Proc Natl Acad Sci U S A. 2009. PMID: 19995970 Free PMC article.
Endocan is upregulated on tumor vessels in invasive bladder cancer where it mediates VEGF-A-induced angiogenesis.
Roudnicky F, Poyet C, Wild P, Krampitz S, Negrini F, Huggenberger R, Rogler A, Stöhr R, Hartmann A, Provenzano M, Otto VI, Detmar M. Roudnicky F, et al. Among authors: huggenberger r. Cancer Res. 2013 Feb 1;73(3):1097-106. doi: 10.1158/0008-5472.CAN-12-1855. Epub 2012 Dec 14. Cancer Res. 2013. PMID: 23243026 Free article.
The cutaneous vascular system in chronic skin inflammation.
Huggenberger R, Detmar M. Huggenberger R, et al. J Investig Dermatol Symp Proc. 2011 Dec;15(1):24-32. doi: 10.1038/jidsymp.2011.5. J Investig Dermatol Symp Proc. 2011. PMID: 22076324 Free PMC article. Review.
An important role of lymphatic vessel activation in limiting acute inflammation.
Huggenberger R, Siddiqui SS, Brander D, Ullmann S, Zimmermann K, Antsiferova M, Werner S, Alitalo K, Detmar M. Huggenberger R, et al. Blood. 2011 Apr 28;117(17):4667-78. doi: 10.1182/blood-2010-10-316356. Epub 2011 Mar 1. Blood. 2011. PMID: 21364190 Free PMC article.
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.
Huggenberger R, Ullmann S, Proulx ST, Pytowski B, Alitalo K, Detmar M. Huggenberger R, et al. J Exp Med. 2010 Sep 27;207(10):2255-69. doi: 10.1084/jem.20100559. Epub 2010 Sep 13. J Exp Med. 2010. PMID: 20837699 Free PMC article.
Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis.
Shin JW, Huggenberger R, Detmar M. Shin JW, et al. Among authors: huggenberger r. Blood. 2008 Sep 15;112(6):2318-26. doi: 10.1182/blood-2008-05-156331. Epub 2008 Jul 9. Blood. 2008. PMID: 18614759 Free PMC article.
An important role of the SDF-1/CXCR4 axis in chronic skin inflammation.
Zgraggen S, Huggenberger R, Kerl K, Detmar M. Zgraggen S, et al. Among authors: huggenberger r. PLoS One. 2014 Apr 2;9(4):e93665. doi: 10.1371/journal.pone.0093665. eCollection 2014. PLoS One. 2014. PMID: 24695674 Free PMC article.
Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo.
Proulx ST, Luciani P, Alitalo A, Mumprecht V, Christiansen AJ, Huggenberger R, Leroux JC, Detmar M. Proulx ST, et al. Among authors: huggenberger r. Angiogenesis. 2013 Jul;16(3):525-40. doi: 10.1007/s10456-013-9332-2. Epub 2013 Jan 17. Angiogenesis. 2013. PMID: 23325334 Free PMC article.
Increased permeability of cutaneous lymphatic capillaries and enhanced blood flow in psoriatic plaques.
Meier TO, Kovacicova L, Huggenberger R, Navarini AA, Gitzelmann G, Amann-Vesti BR. Meier TO, et al. Among authors: huggenberger r. Dermatology. 2013;227(2):118-25. doi: 10.1159/000351878. Epub 2013 Sep 19. Dermatology. 2013. PMID: 24051689 Free article.
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