Huhn S - Search Results

1

Chromosomal instability drives convergent and divergent evolution toward advantageous inherited traits in mammalian CHO bioproduction lineages.

Huhn S, Chang M, Kumar A, Liu R, Jiang B, Betenbaugh M, Lin H, Nyberg G, Du Z. Huhn S, et al. iScience. 2022 Mar 14;25(4):104074. doi: 10.1016/j.isci.2022.104074. eCollection 2022 Apr 15. iScience. 2022. PMID: 35355517 Free PMC article.

2

High throughput, efficacious gene editing & genome surveillance in Chinese hamster ovary cells.

Huhn SC, Ou Y, Kumar A, Liu R, Du Z. Huhn SC, et al. PLoS One. 2019 Dec 19;14(12):e0218653. doi: 10.1371/journal.pone.0218653. eCollection 2019. PLoS One. 2019. PMID: 31856197 Free PMC article.

3

Investigation of the Impact from IL-2, IL-7, and IL-15 on the Growth and Signaling of Activated CD4⁺ T Cells.

Coppola C, Hopkins B, Huhn S, Du Z, Huang Z, Kelly WJ. Coppola C, et al. Among authors: huhn s. Int J Mol Sci. 2020 Oct 22;21(21):7814. doi: 10.3390/ijms21217814. Int J Mol Sci. 2020. PMID: 33105566 Free PMC article.

4

Modulating tyrosine sulfation of recombinant antibodies in CHO cell culture by host selection and sodium chlorate supplementation.

Liu R, Zhang Y, Kumar A, Huhn S, Hullinger L, Du Z. Liu R, et al. Among authors: huhn s. Biotechnol J. 2021 Sep;16(9):e2100142. doi: 10.1002/biot.202100142. Epub 2021 Jun 20. Biotechnol J. 2021. PMID: 34081410

5

Improvement of the efficiency and quality in developing a new CHO host cell line.

Huhn SC, Ou Y, Tang X, Jiang B, Liu R, Lin H, Du Z. Huhn SC, et al. Biotechnol Prog. 2021 Sep;37(5):e3185. doi: 10.1002/btpr.3185. Epub 2021 Jun 26. Biotechnol Prog. 2021. PMID: 34142466

6

Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages.

Chang M, Kumar A, Kumar S, Huhn S, Timp W, Betenbaugh M, Du Z. Chang M, et al. Among authors: huhn s. Biotechnol Bioeng. 2022 Apr;119(4):1062-1076. doi: 10.1002/bit.28036. Epub 2022 Jan 23. Biotechnol Bioeng. 2022. PMID: 35028935

7

Significant impact of mTORC1 and ATF4 pathways in CHO cell recombinant protein production induced by CDK4/6 inhibitor.

Chang M, Huhn S, Nelson L, Betenbaugh M, Du Z. Chang M, et al. Among authors: huhn s. Biotechnol Bioeng. 2022 May;119(5):1189-1206. doi: 10.1002/bit.28050. Epub 2022 Feb 17. Biotechnol Bioeng. 2022. PMID: 35112712

8

A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins.

Zhang Q, Jiang B, Nelson L, Huhn S, Du Z, Chasin LA. Zhang Q, et al. Among authors: huhn s. Biotechnol Bioeng. 2022 Jun;119(6):1392-1404. doi: 10.1002/bit.28074. Epub 2022 Mar 19. Biotechnol Bioeng. 2022. PMID: 35249214

9

Identification of RNA content of CHO-derived extracellular vesicles from a production process.

Busch DJ, Zhang Y, Kumar A, Huhn SC, Du Z, Liu R. Busch DJ, et al. J Biotechnol. 2022 Mar 20;348:36-46. doi: 10.1016/j.jbiotec.2022.03.004. Epub 2022 Mar 12. J Biotechnol. 2022. PMID: 35292346

10

A proteomics approach to decipher a sticky CHO situation.

Kumar S, Kumar A, Huhn S, DeVine L, Cole R, Du Z, Betenbaugh M. Kumar S, et al. Among authors: huhn s. Biotechnol Bioeng. 2022 Aug;119(8):2064-2075. doi: 10.1002/bit.28108. Epub 2022 May 25. Biotechnol Bioeng. 2022. PMID: 35470426 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

160 results

Search Page