Huidobro-Toro JP - Search Results

1

Activation and regulation of purinergic P2X receptor channels.

Coddou C, Yan Z, Obsil T, Huidobro-Toro JP, Stojilkovic SS. Coddou C, et al. Pharmacol Rev. 2011 Sep;63(3):641-83. doi: 10.1124/pr.110.003129. Epub 2011 Jul 7. Pharmacol Rev. 2011. PMID: 21737531 Free PMC article. Review.

2

Allosteric modulation of ATP-gated P2X receptor channels.

Coddou C, Stojilkovic SS, Huidobro-Toro JP. Coddou C, et al. Rev Neurosci. 2011;22(3):335-54. doi: 10.1515/RNS.2011.014. Epub 2011 Mar 16. Rev Neurosci. 2011. PMID: 21639805 Free PMC article. Review.

3

Trace metals in the brain: allosteric modulators of ligand-gated receptor channels, the case of ATP-gated P2X receptors.

Huidobro-Toro JP, Lorca RA, Coddou C. Huidobro-Toro JP, et al. Eur Biophys J. 2008 Mar;37(3):301-14. doi: 10.1007/s00249-007-0230-7. Epub 2007 Oct 31. Eur Biophys J. 2008. PMID: 17972073 Review.

4

Differential role of extracellular histidines in copper, zinc, magnesium and proton modulation of the P2X7 purinergic receptor.

Acuña-Castillo C, Coddou C, Bull P, Brito J, Huidobro-Toro JP. Acuña-Castillo C, et al. J Neurochem. 2007 Apr;101(1):17-26. doi: 10.1111/j.1471-4159.2006.04343.x. J Neurochem. 2007. PMID: 17394459 Free article.

5

Heavy metals modulate the activity of the purinergic P2X4 receptor.

Coddou C, Lorca RA, Acuña-Castillo C, Grauso M, Rassendren F, Huidobro-Toro JP. Coddou C, et al. Toxicol Appl Pharmacol. 2005 Jan 15;202(2):121-31. doi: 10.1016/j.taap.2004.06.015. Toxicol Appl Pharmacol. 2005. PMID: 15629187

6

Reactive oxygen species potentiate the P2X2 receptor activity through intracellular Cys430.

Coddou C, Codocedo JF, Li S, Lillo JG, Acuña-Castillo C, Bull P, Stojilkovic SS, Huidobro-Toro JP. Coddou C, et al. J Neurosci. 2009 Sep 30;29(39):12284-91. doi: 10.1523/JNEUROSCI.2096-09.2009. J Neurosci. 2009. PMID: 19793987 Free PMC article.

7

Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition.

Coddou C, Acuña-Castillo C, Bull P, Huidobro-Toro JP. Coddou C, et al. J Biol Chem. 2007 Dec 21;282(51):36879-86. doi: 10.1074/jbc.M706925200. Epub 2007 Oct 25. J Biol Chem. 2007. PMID: 17962187 Free article.

8

Histidine 140 plays a key role in the inhibitory modulation of the P2X4 nucleotide receptor by copper but not zinc.

Coddou C, Morales B, González J, Grauso M, Gordillo F, Bull P, Rassendren F, Huidobro-Toro JP. Coddou C, et al. J Biol Chem. 2003 Sep 19;278(38):36777-85. doi: 10.1074/jbc.M305177200. Epub 2003 Jun 20. J Biol Chem. 2003. PMID: 12819199 Free article.

9

The hypolipidemic drug metabolites nafenopin-CoA and ciprofibroyl-CoA are competitive P2Y1 receptor antagonists.

Coddou C, Loyola G, Boyer JL, Bronfman M, Huidobro-Toro JP. Coddou C, et al. FEBS Lett. 2003 Feb 11;536(1-3):145-50. doi: 10.1016/s0014-5793(03)00044-9. FEBS Lett. 2003. PMID: 12586354 Free article.

10

Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation.

Lorca RA, Coddou C, Gazitúa MC, Bull P, Arredondo C, Huidobro-Toro JP. Lorca RA, et al. J Neurochem. 2005 Oct;95(2):499-512. doi: 10.1111/j.1471-4159.2005.03387.x. J Neurochem. 2005. PMID: 16190872 Free article.

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