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TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling.
Riera CE, Huising MO, Follett P, Leblanc M, Halloran J, Van Andel R, de Magalhaes Filho CD, Merkwirth C, Dillin A. Riera CE, et al. Among authors: huising mo. Cell. 2014 May 22;157(5):1023-36. doi: 10.1016/j.cell.2014.03.051. Cell. 2014. PMID: 24855942
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner.
Huising MO, van der Meulen T, Vaughan JM, Matsumoto M, Donaldson CJ, Park H, Billestrup N, Vale WW. Huising MO, et al. Proc Natl Acad Sci U S A. 2010 Jan 12;107(2):912-7. doi: 10.1073/pnas.0913610107. Epub 2009 Dec 22. Proc Natl Acad Sci U S A. 2010. PMID: 20080775 Free PMC article.
Glucocorticoids differentially regulate the expression of CRFR1 and CRFR2α in MIN6 insulinoma cells and rodent islets.
Huising MO, Pilbrow AP, Matsumoto M, van der Meulen T, Park H, Vaughan JM, Lee S, Vale WW. Huising MO, et al. Endocrinology. 2011 Jan;152(1):138-50. doi: 10.1210/en.2010-0791. Epub 2010 Nov 24. Endocrinology. 2011. PMID: 21106875 Free PMC article.
The transcriptional landscape of mouse beta cells compared to human beta cells reveals notable species differences in long non-coding RNA and protein-coding gene expression.
Benner C, van der Meulen T, Cacéres E, Tigyi K, Donaldson CJ, Huising MO. Benner C, et al. Among authors: huising mo. BMC Genomics. 2014 Jul 22;15(1):620. doi: 10.1186/1471-2164-15-620. BMC Genomics. 2014. PMID: 25051960 Free PMC article.
Urocortin3 mediates somatostatin-dependent negative feedback control of insulin secretion.
van der Meulen T, Donaldson CJ, Cáceres E, Hunter AE, Cowing-Zitron C, Pound LD, Adams MW, Zembrzycki A, Grove KL, Huising MO. van der Meulen T, et al. Among authors: huising mo. Nat Med. 2015 Jul;21(7):769-76. doi: 10.1038/nm.3872. Epub 2015 Jun 15. Nat Med. 2015. PMID: 26076035 Free PMC article.
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2.
Hogan MF, Ravnskjaer K, Matsumura S, Huising MO, Hull RL, Kahn SE, Montminy M. Hogan MF, et al. Among authors: huising mo. J Biol Chem. 2015 Oct 23;290(43):25997-6006. doi: 10.1074/jbc.M115.679266. Epub 2015 Sep 4. J Biol Chem. 2015. PMID: 26342077 Free PMC article.
Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets.
DiGruccio MR, Mawla AM, Donaldson CJ, Noguchi GM, Vaughan J, Cowing-Zitron C, van der Meulen T, Huising MO. DiGruccio MR, et al. Among authors: huising mo. Mol Metab. 2016 May 3;5(7):449-458. doi: 10.1016/j.molmet.2016.04.007. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408771 Free PMC article.
Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets.
van der Meulen T, Mawla AM, DiGruccio MR, Adams MW, Nies V, Dólleman S, Liu S, Ackermann AM, Cáceres E, Hunter AE, Kaestner KH, Donaldson CJ, Huising MO. van der Meulen T, et al. Among authors: huising mo. Cell Metab. 2017 Apr 4;25(4):911-926.e6. doi: 10.1016/j.cmet.2017.03.017. Cell Metab. 2017. PMID: 28380380
Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.
Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M. Zeng C, et al. Among authors: huising mo. Cell Metab. 2017 May 2;25(5):1160-1175.e11. doi: 10.1016/j.cmet.2017.04.014. Cell Metab. 2017. PMID: 28467932 Free PMC article.
Artemether Does Not Turn α Cells into β Cells.
van der Meulen T, Lee S, Noordeloos E, Donaldson CJ, Adams MW, Noguchi GM, Mawla AM, Huising MO. van der Meulen T, et al. Among authors: huising mo. Cell Metab. 2018 Jan 9;27(1):218-225.e4. doi: 10.1016/j.cmet.2017.10.002. Epub 2017 Nov 2. Cell Metab. 2018. PMID: 29103923 Free PMC article.
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