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Aprepitant inhibits cyclophosphamide bioactivation and thiotepa metabolism.
de Jonge ME, Huitema AD, Holtkamp MJ, van Dam SM, Beijnen JH, Rodenhuis S. de Jonge ME, et al. Among authors: huitema ad. Cancer Chemother Pharmacol. 2005 Oct;56(4):370-8. doi: 10.1007/s00280-005-1005-4. Epub 2005 Apr 19. Cancer Chemother Pharmacol. 2005. PMID: 15838656 Clinical Trial.
Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.
van Kesteren C, Zandvliet AS, Karlsson MO, Mathôt RA, Punt CJ, Armand JP, Raymond E, Huitema AD, Dittrich C, Dumez H, Roché HH, Droz JP, Ravic M, Yule SM, Wanders J, Beijnen JH, Fumoleau P, Schellens JH. van Kesteren C, et al. Among authors: huitema ad. Invest New Drugs. 2005 Jun;23(3):225-34. doi: 10.1007/s10637-005-6730-3. Invest New Drugs. 2005. PMID: 15868378
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