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53 results

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Page 1
Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity.
Lang Y, Li W, Li Z, Koerhuis D, van den Burg ACS, Rozemuller E, Bosch BJ, van Kuppeveld FJM, Boons GJ, Huizinga EG, van der Schaar HM, de Groot RJ. Lang Y, et al. Among authors: huizinga eg. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25759-25770. doi: 10.1073/pnas.2006299117. Epub 2020 Sep 29. Proc Natl Acad Sci U S A. 2020. PMID: 32994342 Free PMC article.
Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain A.
Hulswit RJG, Lang Y, Bakkers MJG, Li W, Li Z, Schouten A, Ophorst B, van Kuppeveld FJM, Boons GJ, Bosch BJ, Huizinga EG, de Groot RJ. Hulswit RJG, et al. Among authors: huizinga eg. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2681-2690. doi: 10.1073/pnas.1809667116. Epub 2019 Jan 24. Proc Natl Acad Sci U S A. 2019. PMID: 30679277 Free PMC article.
Rare variants in GP1BB are responsible for autosomal dominant macrothrombocytopenia.
Sivapalaratnam S, Westbury SK, Stephens JC, Greene D, Downes K, Kelly AM, Lentaigne C, Astle WJ, Huizinga EG, Nurden P, Papadia S, Peerlinck K, Penkett CJ, Perry DJ, Roughley C, Simeoni I, Stirrups K, Hart DP, Tait RC, Mumford AD; NIHR BioResource; Laffan MA, Freson K, Ouwehand WH, Kunishima S, Turro E. Sivapalaratnam S, et al. Among authors: huizinga eg. Blood. 2017 Jan 26;129(4):520-524. doi: 10.1182/blood-2016-08-732248. Epub 2016 Nov 14. Blood. 2017. PMID: 28064200 Free PMC article.
Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
Bakkers MJ, Zeng Q, Feitsma LJ, Hulswit RJ, Li Z, Westerbeke A, van Kuppeveld FJ, Boons GJ, Langereis MA, Huizinga EG, de Groot RJ. Bakkers MJ, et al. Among authors: huizinga eg. Proc Natl Acad Sci U S A. 2016 May 31;113(22):E3111-9. doi: 10.1073/pnas.1519881113. Epub 2016 May 16. Proc Natl Acad Sci U S A. 2016. PMID: 27185912 Free PMC article.
Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).
Koymans KJ, Feitsma LJ, Brondijk TH, Aerts PC, Lukkien E, Lössl P, van Kessel KP, de Haas CJ, van Strijp JA, Huizinga EG. Koymans KJ, et al. Among authors: huizinga eg. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11018-23. doi: 10.1073/pnas.1502026112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283364 Free PMC article.
53 results