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Modulation of chromatin structure by poly(ADP-ribosyl)ation.
de Murcia G, Huletsky A, Poirier GG. de Murcia G, et al. Biochem Cell Biol. 1988 Jun;66(6):626-35. doi: 10.1139/o88-072. Biochem Cell Biol. 1988. PMID: 3139015 Review.
Poly(ADP-ribose) polymerase is a nuclear enzyme that is highly conserved in eucaryotes. Its activity is totally dependent on the presence of DNA containing single or double stranded breaks. We have shown that this activation results in a decondensation of chromatin …
Poly(ADP-ribose) polymerase is a nuclear enzyme that is highly conserved in eucaryotes. Its activity is totally dependent on the pres …
Hyper(ADP-ribosyl)ation of histone H1.
Aubin RJ, Dam VT, Miclette J, Brousseau Y, Huletsky A, Poirier GG. Aubin RJ, et al. Can J Biochem. 1982 Dec;60(12):1085-94. doi: 10.1139/o82-139. Can J Biochem. 1982. PMID: 6299482
Nucleosomal chains of various repeat unit lengths were generated by a mild micrococcal nuclease digestion of purified pancreatic nuclei. ...Furthermore, the extent of ADP-ribosylation present on pancreatic histone H1 is shown to proportionally retard this protein's electro …
Nucleosomal chains of various repeat unit lengths were generated by a mild micrococcal nuclease digestion of purified pancreatic nucl …
Poly(ADP-ribosyl)ation of chromatin: kinetics of relaxation and its effect on chromatin solubility.
Frechette A, Huletsky A, Aubin RJ, de Murcia G, Mandel P, Lord A, Grondin G, Poirier GG. Frechette A, et al. Can J Biochem Cell Biol. 1985 Jul;63(7):764-73. doi: 10.1139/o85-096. Can J Biochem Cell Biol. 1985. PMID: 3930055
A correlation can be established between the appearance of histone H1 modified forms and the localized relaxation of the chromatin. ...
A correlation can be established between the appearance of histone H1 modified forms and the localized relaxation of the chromatin. .
Modulation of chromatin superstructure induced by poly(ADP-ribose) synthesis and degradation.
de Murcia G, Huletsky A, Lamarre D, Gaudreau A, Pouyet J, Daune M, Poirier GG. de Murcia G, et al. J Biol Chem. 1986 May 25;261(15):7011-7. J Biol Chem. 1986. PMID: 3084493
U.S.A. 79, 3423-3427) that poly(ADP-ribosyl)ation of pancreatic nucleosomes causes relaxation of the chromatin superstructure through H1 modification. ...
U.S.A. 79, 3423-3427) that poly(ADP-ribosyl)ation of pancreatic nucleosomes causes relaxation of the chromatin superstructure through …
The effect of poly(ADP-ribosyl)ation on native and H1-depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure.
Huletsky A, de Murcia G, Muller S, Hengartner M, Ménard L, Lamarre D, Poirier GG. Huletsky A, et al. J Biol Chem. 1989 May 25;264(15):8878-86. J Biol Chem. 1989. PMID: 2498319
In native chromatin incubated in the presence of Mg2+ there was a drop in the accessibility of histone epitopes to monoclonal and polyclonal antibodies whereas upon poly(ADP-ribosyl)ation their accessibility was found to remain even in the presence of Mg2+. ...
In native chromatin incubated in the presence of Mg2+ there was a drop in the accessibility of histone epitopes to monoclonal and pol …
Sequential ADP-ribosylation pattern of nucleosomal histones. ADP-ribosylation of nucleosomal histones.
Huletsky A, Niedergang C, Fréchette A, Aubin R, Gaudreau A, Poirier GG. Huletsky A, et al. Eur J Biochem. 1985 Jan 15;146(2):277-85. doi: 10.1111/j.1432-1033.1985.tb08650.x. Eur J Biochem. 1985. PMID: 2981686
However at NAD concentrations above 10 microM the enzyme preferentially poly(ADP-ribosyl)ates histone H1 to a hyper ADP-ribosylated form. ...
However at NAD concentrations above 10 microM the enzyme preferentially poly(ADP-ribosyl)ates histone H1 to a hyper ADP-ribosylated f …
Rapid exonuclease digestion of PCR-amplified targets for improved microarray hybridization.
Boissinot K, Huletsky A, Peytavi R, Turcotte S, Veillette V, Boissinot M, Picard FJ, mARTEL EA, Bergeron MG. Boissinot K, et al. Clin Chem. 2007 Nov;53(11):2020-3. doi: 10.1373/clinchem.2007.091157. Clin Chem. 2007. PMID: 18030700 No abstract available.
Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type beta-lactamases probed by site-directed mutagenesis and three-dimensional modeling.
Huletsky A, Knox JR, Levesque RC. Huletsky A, et al. J Biol Chem. 1993 Feb 15;268(5):3690-7. J Biol Chem. 1993. PMID: 8429044
A growing number of extended spectrum SHV-type beta-lactamases capable of hydrolyzing third-generation cephalosporins such as cefotaxime and ceftazidime have been reported. These new enzymes differ by a few amino acids from SHV-1, an enzyme incapable of hydrolyzing
A growing number of extended spectrum SHV-type beta-lactamases capable of hydrolyzing third-generation cephalosporins such as cefotax
Analytical limits of three beta-glucosidase-based commercial culture methods used in environmental microbiology, to detect enterococci.
Maheux AF, Picard FJ, Boissinot M, Huppé V, Bissonnette L, Bernier JL, Cantin P, Huletsky A, Bergeron MG. Maheux AF, et al. Among authors: huletsky a. Water Sci Technol. 2009;60(4):943-55. doi: 10.2166/wst.2009.428. Water Sci Technol. 2009. PMID: 19700833
Plastic polymers for efficient DNA microarray hybridization: application to microbiological diagnostics.
Zhao Z, Peytavi R, Diaz-Quijada GA, Picard FJ, Huletsky A, Leblanc E, Frenette J, Boivin G, Veres T, Dumoulin MM, Bergeron MG. Zhao Z, et al. Among authors: huletsky a. J Clin Microbiol. 2008 Nov;46(11):3752-8. doi: 10.1128/JCM.00377-08. Epub 2008 Sep 10. J Clin Microbiol. 2008. PMID: 18784318 Free PMC article.
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