Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2004 1
2005 4
2006 1
2008 1
2009 1
2013 2
2016 1
2017 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

13 results

Results by year

Citations

1 article found by citation matching

Search results

Filters applied: . Clear all
Page 1
Human peripheral blood mononuclear cells transfected with messenger RNA stimulate antigen-specific cytotoxic T-lymphocytes in vitro.
Teufel R, Carralot JP, Scheel B, Probst J, Walter S, Jung G, Hoerr I, Rammensee HG, Pascolo S. Teufel R, et al. Cell Mol Life Sci. 2005 Aug;62(15):1755-62. doi: 10.1007/s00018-005-5067-6. Cell Mol Life Sci. 2005. PMID: 16003494 Free PMC article.
Their production typically requires samples of 100 ml blood from the patients, and limits the number of assays that can be performed. We show here that fresh peripheral blood mononuclear cells (PBMCs) can be transfected with mRNA by elect …
Their production typically requires samples of 100 ml blood from the patients, and limits the number of assays that can be performed. …
Increased cytotoxic capacity of tumor antigen specific human T cells after in vitro stimulation with IL21 producing dendritic cells.
Turksma AW, Bontkes HJ, Ruizendaal JJ, van den Heuvel H, Scholten KB, Santegoets SJ, de Gruijl TD, Meijer CJ, Hooijberg E. Turksma AW, et al. Hum Immunol. 2013 May;74(5):506-13. doi: 10.1016/j.humimm.2013.01.014. Epub 2013 Jan 29. Hum Immunol. 2013. PMID: 23376456
IL21 has been shown to enhance activation and cytotoxicity in CD8+ T cells. We therefore investigated in vitro effects on human CD8+ T-cells after stimulation with IL21 mRNA electroporated moDC. ...Tumor associated antigen speci …
IL21 has been shown to enhance activation and cytotoxicity in CD8+ T cells. We therefore investigated in vitro effects …
Induction of antigen-specific cytotoxic T lymphocytes by using monocyte-derived DCs transfected with in vitro-transcribed WT1 or SART1 mRNA.
Narita M, Tochiki N, Saitoh A, Watanabe N, Kaji M, Satoh N, Yamahira A, Nakamura T, Masuko M, Furukawa T, Toba K, Fuse I, Aizawa Y, Takahashi M. Narita M, et al. Med Oncol. 2009 Dec;26(4):429-36. doi: 10.1007/s12032-008-9142-3. Epub 2008 Dec 5. Med Oncol. 2009. PMID: 19058036
To evaluate the usefulness of monocyte-derived dendritic cells transfected with tumor antigen mRNA for dendritic cell-based antitumor immunotherapy, we attempted to generate antigen-specific cytotoxic T cells by priming lymphocytes with m …
To evaluate the usefulness of monocyte-derived dendritic cells transfected with tumor antigen mRNA for dendritic cell-based an …
Generation of Ag-specific cytotoxic T lymphocytes by DC transfected with in vitro transcribed influenza virus matrix protein (M1) mRNA.
Osman Y, Narita M, Ayres F, Takahashi M, Alldawi L, Tatsuo F, Toba K, Hirohashi T, Aizawa Y. Osman Y, et al. Cytotherapy. 2003;5(2):161-8. doi: 10.1080/14653240310001064. Cytotherapy. 2003. PMID: 12745578
BACKGROUND: Application of DC transfected with tumor Ag RNA is promising for DC-based tumor immunotherapy. In this study, Ag-specific cytotoxic T lymphocytes (CTL) were generated by priming lymphocytes with DC transfected with in …
BACKGROUND: Application of DC transfected with tumor Ag RNA is promising for DC-based tumor immunotherapy. In this study, Ag-s …
Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes.
Grünebach F, Kayser K, Weck MM, Müller MR, Appel S, Brossart P. Grünebach F, et al. Cancer Gene Ther. 2005 Sep;12(9):749-56. doi: 10.1038/sj.cgt.7700842. Cancer Gene Ther. 2005. PMID: 15877082
Therefore in vitro generated human monocyte-derived DCs were electroporated with in vitro transcribed RNA (in vitro transcript, IVT) encoding the TAA HER-2/neu. ...The here established approach of cotransfection of DCs with …
Therefore in vitro generated human monocyte-derived DCs were electroporated with in vitro transcribed …
Delivery of tumor-derived RNA for the induction of cytotoxic T-lymphocytes.
Grünebach F, Müller MR, Nencioni A, Brossart P. Grünebach F, et al. Gene Ther. 2003 Mar;10(5):367-74. doi: 10.1038/sj.gt.3301901. Gene Ther. 2003. PMID: 12601391
Dendritic cells (DC) are professional antigen-presenting cells playing a central role in the induction of antigen-specific cytotoxic T-lymphocytes (CTL). ...To evaluate the sensitivity of these approaches, we utilized in …
Dendritic cells (DC) are professional antigen-presenting cells playing a central role in the induction of antigen-sp …
Induction of cytotoxic T-lymphocyte responses using dendritic cells transfected with hepatocellular carcinoma mRNA.
Peng BG, He Q, Liang LI, Xie BH, Hua YP, Chen ZB, Zhou F. Peng BG, et al. Br J Biomed Sci. 2006;63(3):123-8. doi: 10.1080/09674845.2006.11732731. Br J Biomed Sci. 2006. PMID: 17058712
This study aims to induce an efficient expansion of cytotoxic T-lymphocytes (CTL) from peripheral blood mononuclear cells (PBMCs) using dendritic cells (DC) transfected with hepatocellular carcinoma (HCC) messenger …
This study aims to induce an efficient expansion of cytotoxic T-lymphocytes (CTL) from peripheral blood …
RNA-transfection of gamma/delta T cells with a chimeric antigen receptor or an alpha/beta T-cell receptor: a safer alternative to genetically engineered alpha/beta T cells for the immunotherapy of melanoma.
Harrer DC, Simon B, Fujii SI, Shimizu K, Uslu U, Schuler G, Gerer KF, Hoyer S, Dörrie J, Schaft N. Harrer DC, et al. BMC Cancer. 2017 Aug 17;17(1):551. doi: 10.1186/s12885-017-3539-3. BMC Cancer. 2017. PMID: 28818060 Free PMC article.
Upon respective stimulation, gamma/delta T cells produced IFNgamma and TNF, but little IL-2 and the zoledronic-acid expanded T cells exceeded MACS-gamma/delta T cells in antigen-specific cytokine secretion. ...After transfection, g …
Upon respective stimulation, gamma/delta T cells produced IFNgamma and TNF, but little IL-2 and the zoledronic-acid expanded T …
Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy.
Devi GR, Nath S. Devi GR, et al. Methods Mol Biol. 2016;1428:231-43. doi: 10.1007/978-1-4939-3625-0_15. Methods Mol Biol. 2016. PMID: 27236803
To prepare vaccines, DCs are pulsed or transfected with either: (a) defined peptides of tumor-associated antigens, (b) total protein isolated from the tumor cell, (c) autologous total RNA isolated from the tumor cell, (d) synthetic tumor-antigen-encoding mRNA, or (e …
To prepare vaccines, DCs are pulsed or transfected with either: (a) defined peptides of tumor-associated antigens, (b) total protein …
Enhanced induction of telomerase-specific CD4(+) T cells using dendritic cells transfected with RNA encoding a chimeric gene product.
Su Z, Vieweg J, Weizer AZ, Dahm P, Yancey D, Turaga V, Higgins J, Boczkowski D, Gilboa E, Dannull J. Su Z, et al. Cancer Res. 2002 Sep 1;62(17):5041-8. Cancer Res. 2002. PMID: 12208759
In this study, we sought to determine whether human DCs transfected with mRNA encoding a chimeric hTERT/lysosome-associated membrane protein (LAMP-1) protein, carrying the endosomal/lysosomal sorting signal of the LAMP-1, are capable of stimulating concomitan …
In this study, we sought to determine whether human DCs transfected with mRNA encoding a chimeric hTERT/lysosome-associated me …
13 results