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Page 1
P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells.
Jones DA, Abbassi O, McIntire LV, McEver RP, Smith CW. Jones DA, et al. Biophys J. 1993 Oct;65(4):1560-9. doi: 10.1016/S0006-3495(93)81195-0. Biophys J. 1993. PMID: 7506064 Free PMC article.
Monoclonal antibody (MAb) G1, which binds P-selectin and blocks its adhesive function, completely prevents association of the PMNs with histamine-stimulated HUVEC, whereas the nonblocking anti-P-selectin MAb S12 does not. Treatment of PMNs with the anti-L-selectin M …
Monoclonal antibody (MAb) G1, which binds P-selectin and blocks its adhesive function, completely prevents association of the PMNs with hist …
L-selectin from human, but not from mouse neutrophils binds directly to E-selectin.
Zöllner O, Lenter MC, Blanks JE, Borges E, Steegmaier M, Zerwes HG, Vestweber D. Zöllner O, et al. J Cell Biol. 1997 Feb 10;136(3):707-16. doi: 10.1083/jcb.136.3.707. J Cell Biol. 1997. PMID: 9024699 Free PMC article.
Binding of human L-selectin to E-selectin was direct, since purified L-selectin could be reprecipitated with E-selectin-Ig. ...No such inhibitory effect was seen with the anti-mouse L-selectin mAb MEL14 on mouse neutrophils. Rollin …
Binding of human L-selectin to E-selectin was direct, since purified L-selectin could be reprecipitated w …
Ruminant cluster CD62L.
Howard CJ. Howard CJ. Vet Immunol Immunopathol. 1996 Aug;52(4):255-6. doi: 10.1016/0165-2427(96)05571-7. Vet Immunol Immunopathol. 1996. PMID: 8896209
Immunol., 77:228-234) by showing that human L-selectin mAb LAM1.4 (Spertini, O., Kansas, G.S., Reimann, K.A., Mackay, C.R. and Tedder, T.F., 1991. ...Immunol., 147:942) cross-reacts with bovine cells and blocks binding of IAH-CC32. The mAb DREG-56 to human …
Immunol., 77:228-234) by showing that human L-selectin mAb LAM1.4 (Spertini, O., Kansas, G.S., Reimann, K.A., Mackay, C …
Neuropeptides promote neutrophil adherence to endothelial cell monolayers.
Zimmerman BJ, Anderson DC, Granger DN. Zimmerman BJ, et al. Am J Physiol. 1992 Nov;263(5 Pt 1):G678-82. doi: 10.1152/ajpgi.1992.263.5.G678. Am J Physiol. 1992. PMID: 1279983
Monoclonal antibodies (MAb) directed against the leukocyte adhesion glycoproteins CD11/CD18 (MAb IB4) and L-selectin (MAb DREG56) did not attenuate substance P-induced adhesion. Antibodies directed against the endothelial cell adhesion molecules E-selectin (M …
Monoclonal antibodies (MAb) directed against the leukocyte adhesion glycoproteins CD11/CD18 (MAb IB4) and L-selectin (MAb D …
Molecular mechanisms of L-selectin-induced co-localization in rafts and shedding [corrected].
Phong MC, Gutwein P, Kadel S, Hexel K, Altevogt P, Linderkamp O, Brenner B. Phong MC, et al. Biochem Biophys Res Commun. 2003 Jan 10;300(2):563-9. doi: 10.1016/s0006-291x(02)02886-3. Biochem Biophys Res Commun. 2003. PMID: 12504120
To study intracellular mechanisms, we induced shedding of L-selectin by cross-linking with an immobilized L-selectin antibody (Dreg56) in Jurkat cells. ...Dreg56 cross-linking enhanced phosphorylation and recruitment of L-select …
To study intracellular mechanisms, we induced shedding of L-selectin by cross-linking with an immobilized L-selectin …
Anti-L-selectin aptamers: binding characteristics, pharmacokinetic parameters, and activity against an intravascular target in vivo.
Watson SR, Chang YF, O'Connell D, Weigand L, Ringquist S, Parma DH. Watson SR, et al. Antisense Nucleic Acid Drug Dev. 2000 Apr;10(2):63-75. doi: 10.1089/oli.1.2000.10.63. Antisense Nucleic Acid Drug Dev. 2000. PMID: 10805157
To identify parameters that are important for the in vivo activity of aptamers acting on intravascular targets, we have studied binding characteristics in vitro, pharmacokinetic parameters in Sprague-Dawley rats, and inhibitory activity in a SCID mouse/human lymphocyte mod …
To identify parameters that are important for the in vivo activity of aptamers acting on intravascular targets, we have studied binding char …
Functional and phenotypic characterization of monoclonal antibodies to bovine L-selectin.
Wang Y, Paape MJ, Leino L, Capuco AV, Närvä H. Wang Y, et al. Am J Vet Res. 1997 Dec;58(12):1392-401. Am J Vet Res. 1997. PMID: 9401687 Free article.
Molecular mass of corresponding cell surface antigens also was determined, as was binding of human L-selectin MAB DREG56 to molecules recognized by MAB 11G10 and 2G8 on the surface of bovine neutrophils. ...CONCLUSION: MAB 11G10 and 2G8 recognized L …
Molecular mass of corresponding cell surface antigens also was determined, as was binding of human L-selectin MAB DR …
Anti-L-selectin oligonucleotide ligands recognize CD62L-positive leukocytes: binding affinity and specificity of univalent and bivalent ligands.
Ringquist S, Parma D. Ringquist S, et al. Cytometry. 1998 Dec 1;33(4):394-405. doi: 10.1002/(sici)1097-0320(19981201)33:4<394::aid-cyto2>3.0.co;2-0. Cytometry. 1998. PMID: 9845433 Free article.
Oligonucleotide aptamers generated against purified LS-Rg, a human L-selectin/IgG fusion protein, bound human CD62L-positive leukocytes. FACS analysis of lymphocytes or neutrophils stained with fluorescently labeled aptamers indicated specificit …
Oligonucleotide aptamers generated against purified LS-Rg, a human L-selectin/IgG fusion protein, bound human …
Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways.
Aisa Y, Miyakawa Y, Nakazato T, Shibata H, Saito K, Ikeda Y, Kizaki M. Aisa Y, et al. Am J Hematol. 2005 Jan;78(1):7-14. doi: 10.1002/ajh.20182. Am J Hematol. 2005. PMID: 15609279 Free article.
In contrast, phosphorylation of p38 and Akt was not altered by treatment with fucoidan. L-selectin and P-selectin are known to be receptors of fucoidan; however, as HS-Sultan does not express either of these selectins, it is unlikely that fucoidan induced apoptosis …
In contrast, phosphorylation of p38 and Akt was not altered by treatment with fucoidan. L-selectin and P-selectin are known to …
L-selectin shear thresholding modulates leukocyte secondary capture.
Paschall CD, Lawrence MB. Paschall CD, et al. Ann Biomed Eng. 2008 Apr;36(4):622-31. doi: 10.1007/s10439-008-9468-1. Epub 2008 Feb 26. Ann Biomed Eng. 2008. PMID: 18299990 Free PMC article.
Interestingly, PSGL-1-L-selectin interactions also mediate leukocyte hydrodynamic shear thresholding, whereby leukocyte rolling on purified L-selectin ligands such as PSGL-1 is maximized at a wall shear stress of approximately 1 dyne/cm(2) and minimize …
Interestingly, PSGL-1-L-selectin interactions also mediate leukocyte hydrodynamic shear thresholding, whereby leukocyte rollin …
26 results