Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1982 3
1983 6
1984 5
1985 4
1986 2
1989 2
1991 1
1993 1
1994 2
1995 4
1996 5
1997 9
1998 6
1999 16
2000 12
2001 19
2002 11
2003 15
2004 9
2005 5
2006 7
2007 11
2008 5
2009 11
2010 5
2011 4
2012 3
2013 4
2014 7
2015 8
2016 1
2017 2
2018 1
2019 1
2020 4
2021 2
2022 1
2023 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

205 results

Results by year

Filters applied: . Clear all
Page 1
Thermodynamic Evolution of a Metamorphic Protein: A Theoretical-Computational Study of Human Lymphotactin.
Zanetti-Polzi L, Daidone I, Iacobucci C, Amadei A. Zanetti-Polzi L, et al. Protein J. 2023 Jun;42(3):219-228. doi: 10.1007/s10930-023-10123-7. Epub 2023 May 26. Protein J. 2023. PMID: 37233895 Free PMC article.
Metamorphic, or fold-switching, proteins feature different folds that are physiologically relevant. The human chemokine XCL1 (or Lymphotactin) is a metamorphic protein that features two native states, an [Formula: see text] and an all[Formula: see text] fold, which …
Metamorphic, or fold-switching, proteins feature different folds that are physiologically relevant. The human chemokine XCL1 (or L
Lymphotactin.
Hedrick JA, Zlotnik A. Hedrick JA, et al. Clin Immunol Immunopathol. 1998 Jun;87(3):218-22. doi: 10.1006/clin.1998.4546. Clin Immunol Immunopathol. 1998. PMID: 9646830 Review. No abstract available.
The herpesvirus 8 encoded chemokines vCCL2 (vMIP-II) and vCCL3 (vMIP-III) target the human but not the murine lymphotactin receptor.
Lüttichau HR. Lüttichau HR. Virol J. 2008 Apr 21;5:50. doi: 10.1186/1743-422X-5-50. Virol J. 2008. PMID: 18426556 Free PMC article.
Therefore these virally endcoded chemokines have the potential to be used as tools in the study of lymphotactin receptor pathways in murine models. RESULTS: The activities of vCCL2, vCCL3, human lymphotactin (XCL1) and murine lymphotactin (mXCL1) were …
Therefore these virally endcoded chemokines have the potential to be used as tools in the study of lymphotactin receptor pathways in …
Efficient targeting of NY-ESO-1 tumor antigen to human cDC1s by lymphotactin results in cross-presentation and antigen-specific T cell expansion.
Le Gall C, Cammarata A, de Haas L, Ramos-Tomillero I, Cuenca-Escalona J, Schouren K, Wijfjes Z, Becker AMD, Bödder J, Dölen Y, de Vries IJM, Figdor CG, Flórez-Grau G, Verdoes M. Le Gall C, et al. J Immunother Cancer. 2022 Apr;10(4):e004309. doi: 10.1136/jitc-2021-004309. J Immunother Cancer. 2022. PMID: 35428705 Free PMC article.
Due to its restricted expression and endocytic nature, XCR1 represents an attractive receptor to mediate antigen-delivery to human cDC1s. METHODS: To explore tumor antigen delivery to human cDC1s, we used an engineered version of XCR1-binding lymphotactin (XC …
Due to its restricted expression and endocytic nature, XCR1 represents an attractive receptor to mediate antigen-delivery to human cD …
Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis.
Zavala-Flores LM, Villatoro-Hernandez J, Gamez-Escobedo A, Franco-Molina M, Rangel-Colmenero BR, Villanueva-Olivo A, Gutierrez-Puente Y, de Oca-Luna RM, Valdés-Flores J, Saucedo-Cardenas O. Zavala-Flores LM, et al. Biotechnol Lett. 2009 Feb;31(2):215-20. doi: 10.1007/s10529-008-9855-6. Epub 2008 Oct 16. Biotechnol Lett. 2009. PMID: 18923910
Lymphotactin-XCL1 is a chemokine produced mainly by activated CD8+ T-cells and directs migration of CD4+ and CD8+ lymphocytes and natural killer (NK) cells. We expressed human lymphotactin (LTN) by the lactic-acid bacterium Lactococcus lactis. ...
Lymphotactin-XCL1 is a chemokine produced mainly by activated CD8+ T-cells and directs migration of CD4+ and CD8+ lymphocytes and nat
Chemotactic mediators.
Atkins PC, Wasserman SI. Atkins PC, et al. Clin Rev Allergy. 1983 Sep;1(3):385-95. doi: 10.1007/BF02991228. Clin Rev Allergy. 1983. PMID: 6370407 Review. No abstract available.
The C-class chemokine lymphotactin costimulates the apoptosis of human CD4(+) T cells.
Cerdan C, Devilard E, Xerri L, Olive D. Cerdan C, et al. Blood. 2001 Apr 15;97(8):2205-12. doi: 10.1182/blood.v97.8.2205. Blood. 2001. PMID: 11290580 Free article.
The CD3/TcR pathway induces cell death, mostly when triggered in the absence of costimulatory signal. The unique T cell-specific chemokine of the C class, lymphotactin (Lptn), has recently been shown to inhibit the production of Th1-type lymphokines in human CD4(+) …
The CD3/TcR pathway induces cell death, mostly when triggered in the absence of costimulatory signal. The unique T cell-specific chemokine o …
Interplay of Electrostatics and Hydrophobic Effects in the Metamorphic Protein Human Lymphotactin.
Korkmaz EN, Volkman BF, Cui Q. Korkmaz EN, et al. J Phys Chem B. 2015 Jul 30;119(30):9547-58. doi: 10.1021/acs.jpcb.5b02810. Epub 2015 Jul 16. J Phys Chem B. 2015. PMID: 26134347
The human lymphotactin (hLtn) is a protein that features two native states both of which are physiologically relevant: it is a monomer (hLtn10) at 10 C with 200 mM salt and a dimer (hLtn40) at 40 C and without salt. ...
The human lymphotactin (hLtn) is a protein that features two native states both of which are physiologically relevant: it is a …
Chapter 3. Lymphotactin structural dynamics.
Volkman BF, Liu TY, Peterson FC. Volkman BF, et al. Methods Enzymol. 2009;461:51-70. doi: 10.1016/S0076-6879(09)05403-2. Methods Enzymol. 2009. PMID: 19480914 Free PMC article.
Lymphotactin/XCL1, the defining member of the C class of chemokines, undergoes a conformational change that involves the complete restructuring of all stabilizing interactions. ...We developed methods for resolving the two species and investigated the dynamics of human
Lymphotactin/XCL1, the defining member of the C class of chemokines, undergoes a conformational change that involves the complete res
Lymphotactin: how a protein can adopt two folds.
Camilloni C, Sutto L. Camilloni C, et al. J Chem Phys. 2009 Dec 28;131(24):245105. doi: 10.1063/1.3276284. J Chem Phys. 2009. PMID: 20059117
Metamorphic proteins such as lymphotactin are a notable exception of the empirical principle that structured natural proteins possess a unique three-dimensional structure. In particular, the human chemokine lymphotactin protein exists in two distinct conforma …
Metamorphic proteins such as lymphotactin are a notable exception of the empirical principle that structured natural proteins possess …
205 results