Humphries JD - Search Results

1

Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly.

Horton ER, Byron A, Askari JA, Ng DHJ, Millon-Frémillon A, Robertson J, Koper EJ, Paul NR, Warwood S, Knight D, Humphries JD, Humphries MJ. Horton ER, et al. Among authors: humphries jd, humphries mj. Nat Cell Biol. 2015 Dec;17(12):1577-1587. doi: 10.1038/ncb3257. Epub 2015 Oct 19. Nat Cell Biol. 2015. PMID: 26479319 Free PMC article.

2

Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit.

Humphries JD, Askari JA, Zhang XP, Takada Y, Humphries MJ, Mould AP. Humphries JD, et al. Among authors: humphries mj. J Biol Chem. 2000 Jul 7;275(27):20337-45. doi: 10.1074/jbc.M000568200. J Biol Chem. 2000. PMID: 10764747 Free article.

3

An unraveling tale of how integrins are activated from within.

Travis MA, Humphries JD, Humphries MJ. Travis MA, et al. Among authors: humphries jd, humphries mj. Trends Pharmacol Sci. 2003 Apr;24(4):192-7. doi: 10.1016/S0165-6147(03)00069-5. Trends Pharmacol Sci. 2003. PMID: 12707006 Review.

4

Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins.

Bax DV, Bernard SE, Lomas A, Morgan A, Humphries J, Shuttleworth CA, Humphries MJ, Kielty CM. Bax DV, et al. J Biol Chem. 2003 Sep 5;278(36):34605-16. doi: 10.1074/jbc.M303159200. Epub 2003 Jun 13. J Biol Chem. 2003. PMID: 12807887 Free article.

5

Dual functionality of the anti-beta1 integrin antibody, 12G10, exemplifies agonistic signalling from the ligand binding pocket of integrin adhesion receptors.

Humphries JD, Schofield NR, Mostafavi-Pour Z, Green LJ, Garratt AN, Mould AP, Humphries MJ. Humphries JD, et al. Among authors: humphries mj. J Biol Chem. 2005 Mar 18;280(11):10234-43. doi: 10.1074/jbc.M411102200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632175 Free PMC article.

6

Integrin ligands at a glance.

Humphries JD, Byron A, Humphries MJ. Humphries JD, et al. Among authors: humphries mj. J Cell Sci. 2006 Oct 1;119(Pt 19):3901-3. doi: 10.1242/jcs.03098. J Cell Sci. 2006. PMID: 16988024 Free PMC article. Review. No abstract available.

7

CD14 is a ligand for the integrin alpha4beta1.

Humphries JD, Humphries MJ. Humphries JD, et al. Among authors: humphries mj. FEBS Lett. 2007 Feb 20;581(4):757-63. doi: 10.1016/j.febslet.2007.01.038. Epub 2007 Jan 25. FEBS Lett. 2007. PMID: 17274987 Free article.

8

The alternatively spliced type III connecting segment of fibronectin is a zinc-binding module.

Askari JA, Thornton DJ, Humphries JD, Buckley PA, Humphries MJ. Askari JA, et al. Among authors: humphries jd, humphries mj. Matrix Biol. 2007 Jul;26(6):485-93. doi: 10.1016/j.matbio.2007.04.001. Epub 2007 Apr 6. Matrix Biol. 2007. PMID: 17490871 Free PMC article.

9

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

Humphries JD, Wang P, Streuli C, Geiger B, Humphries MJ, Ballestrem C. Humphries JD, et al. Among authors: humphries mj. J Cell Biol. 2007 Dec 3;179(5):1043-57. doi: 10.1083/jcb.200703036. J Cell Biol. 2007. PMID: 18056416 Free PMC article.

10

Quantification of integrin receptor agonism by fluorescence lifetime imaging.

Parsons M, Messent AJ, Humphries JD, Deakin NO, Humphries MJ. Parsons M, et al. Among authors: humphries jd, humphries mj. J Cell Sci. 2008 Feb 1;121(Pt 3):265-71. doi: 10.1242/jcs.018440. J Cell Sci. 2008. PMID: 18216331 Free PMC article.

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