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POU1F1-mediated activation of hGH-N by deoxyribonuclease I hypersensitive site II of the human growth hormone locus control region.
Hunsaker TL, Jefferson HS, Morrison JK, Franklin AJ, Shewchuk BM. Hunsaker TL, et al. J Mol Biol. 2012 Jan 6;415(1):29-45. doi: 10.1016/j.jmb.2011.11.001. Epub 2011 Nov 9. J Mol Biol. 2012. PMID: 22094313
Proteomic analysis of coregulators bound to ERα on DNA and nucleosomes reveals coregulator dynamics.
Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O'Malley BW. Foulds CE, et al. Among authors: hunsaker tl. Mol Cell. 2013 Jul 25;51(2):185-99. doi: 10.1016/j.molcel.2013.06.007. Epub 2013 Jul 11. Mol Cell. 2013. PMID: 23850489 Free PMC article.
GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP).
Romero FA, Murray J, Lai KW, Tsui V, Albrecht BK, An L, Beresini MH, de Leon Boenig G, Bronner SM, Chan EW, Chen KX, Chen Z, Choo EF, Clagg K, Clark K, Crawford TD, Cyr P, de Almeida Nagata D, Gascoigne KE, Grogan JL, Hatzivassiliou G, Huang W, Hunsaker TL, Kaufman S, Koenig SG, Li R, Li Y, Liang X, Liao J, Liu W, Ly J, Maher J, Masui C, Merchant M, Ran Y, Taylor AM, Wai J, Wang F, Wei X, Yu D, Zhu BY, Zhu X, Magnuson S. Romero FA, et al. Among authors: hunsaker tl. J Med Chem. 2017 Nov 22;60(22):9162-9183. doi: 10.1021/acs.jmedchem.7b00796. Epub 2017 Sep 21. J Med Chem. 2017. PMID: 28892380
Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300.
Crawford TD, Romero FA, Lai KW, Tsui V, Taylor AM, de Leon Boenig G, Noland CL, Murray J, Ly J, Choo EF, Hunsaker TL, Chan EW, Merchant M, Kharbanda S, Gascoigne KE, Kaufman S, Beresini MH, Liao J, Liu W, Chen KX, Chen Z, Conery AR, Côté A, Jayaram H, Jiang Y, Kiefer JR, Kleinheinz T, Li Y, Maher J, Pardo E, Poy F, Spillane KL, Wang F, Wang J, Wei X, Xu Z, Xu Z, Yen I, Zawadzke L, Zhu X, Bellon S, Cummings R, Cochran AG, Albrecht BK, Magnuson S. Crawford TD, et al. Among authors: hunsaker tl. J Med Chem. 2016 Dec 8;59(23):10549-10563. doi: 10.1021/acs.jmedchem.6b01022. Epub 2016 Sep 28. J Med Chem. 2016. PMID: 27682507
A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3.
Lahtela J, Corson LB, Hemmes A, Brauer MJ, Koopal S, Lee J, Hunsaker TL, Jackson PK, Verschuren EW. Lahtela J, et al. Among authors: hunsaker tl. Cell Cycle. 2013 Feb 15;12(4):625-34. doi: 10.4161/cc.23515. Epub 2013 Jan 16. Cell Cycle. 2013. PMID: 23324396 Free PMC article.
Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification.
Nakada Y, Hunsaker TL, Henke RM, Johnson JE. Nakada Y, et al. Among authors: hunsaker tl. Development. 2004 Mar;131(6):1319-30. doi: 10.1242/dev.01008. Development. 2004. PMID: 14993186 Free article.
Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation.
Ebert PJ, Timmer JR, Nakada Y, Helms AW, Parab PB, Liu Y, Hunsaker TL, Johnson JE. Ebert PJ, et al. Among authors: hunsaker tl. Development. 2003 May;130(9):1949-59. doi: 10.1242/dev.00419. Development. 2003. PMID: 12642498 Free article.
Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons.
Gowan K, Helms AW, Hunsaker TL, Collisson T, Ebert PJ, Odom R, Johnson JE. Gowan K, et al. Among authors: hunsaker tl. Neuron. 2001 Aug 2;31(2):219-32. doi: 10.1016/s0896-6273(01)00367-1. Neuron. 2001. PMID: 11502254 Free article.
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