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Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.
Rudman SM, Josephs DH, Cambrook H, Karagiannis P, Gilbert AE, Dodev T, Hunt J, Koers A, Montes A, Taams L, Canevari S, Figini M, Blower PJ, Beavil AJ, Nicodemus CF, Corrigan C, Kaye SB, Nestle FO, Gould HJ, Spicer JF, Karagiannis SN. Rudman SM, et al. Among authors: hunt j. Clin Exp Allergy. 2011 Oct;41(10):1400-13. doi: 10.1111/j.1365-2222.2011.03770.x. Epub 2011 May 16. Clin Exp Allergy. 2011. PMID: 21569129
Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells.
Karagiannis SN, Bracher MG, Beavil RL, Beavil AJ, Hunt J, McCloskey N, Thompson RG, East N, Burke F, Sutton BJ, Dombrowicz D, Balkwill FR, Gould HJ. Karagiannis SN, et al. Among authors: hunt j. Cancer Immunol Immunother. 2008 Feb;57(2):247-63. doi: 10.1007/s00262-007-0371-7. Epub 2007 Jul 27. Cancer Immunol Immunother. 2008. PMID: 17657488
Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells.
Karagiannis P, Singer J, Hunt J, Gan SK, Rudman SM, Mechtcheriakova D, Knittelfelder R, Daniels TR, Hobson PS, Beavil AJ, Spicer J, Nestle FO, Penichet ML, Gould HJ, Jensen-Jarolim E, Karagiannis SN. Karagiannis P, et al. Among authors: hunt j. Cancer Immunol Immunother. 2009 Jun;58(6):915-30. doi: 10.1007/s00262-008-0607-1. Epub 2008 Oct 22. Cancer Immunol Immunother. 2009. PMID: 18941743 Free PMC article.
3,680 results