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Prostaglandin D2 and leukotriene E4 synergize to stimulate diverse TH2 functions and TH2 cell/neutrophil crosstalk.
Xue L, Fergusson J, Salimi M, Panse I, Ussher JE, Hegazy AN, Vinall SL, Jackson DG, Hunter MG, Pettipher R, Ogg G, Klenerman P. Xue L, et al. Among authors: Hunter MG. J Allergy Clin Immunol. 2015 May;135(5):1358-66.e1-11. doi: 10.1016/j.jaci.2014.09.006. Epub 2014 Oct 19. J Allergy Clin Immunol. 2015. PMID: 25441644 Free PMC article.
Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.
Pettipher R, Vinall SL, Xue L, Speight G, Townsend ER, Gazi L, Whelan CJ, Armer RE, Payton MA, Hunter MG. Pettipher R, et al. Among authors: Hunter MG. J Pharmacol Exp Ther. 2012 Feb;340(2):473-82. doi: 10.1124/jpet.111.187203. Epub 2011 Nov 21. J Pharmacol Exp Ther. 2012. PMID: 22106101
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.
Armer RE, Ashton MR, Boyd EA, Brennan CJ, Brookfield FA, Gazi L, Gyles SL, Hay PA, Hunter MG, Middlemiss D, Whittaker M, Xue L, Pettipher R. Armer RE, et al. Among authors: Hunter MG. J Med Chem. 2005 Oct 6;48(20):6174-7. doi: 10.1021/jm050519b. J Med Chem. 2005. PMID: 16190744
Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459.
Pettipher R, Hunter MG, Perkins CM, Collins LP, Lewis T, Baillet M, Steiner J, Bell J, Payton MA. Pettipher R, et al. Among authors: Hunter MG. Allergy. 2014 Sep;69(9):1223-32. doi: 10.1111/all.12451. Epub 2014 Jul 14. Allergy. 2014. PMID: 24866478 Clinical Trial.
Expression of renin-angiotensin system components in the early bovine embryo.
Pijacka W, Hunter MG, Broughton Pipkin F, Luck MR. Pijacka W, et al. Among authors: Hunter MG. Endocr Connect. 2012 Jun 21;1(1):22-30. doi: 10.1530/EC-12-0013. Print 2012 Jul 1. Endocr Connect. 2012. PMID: 23781300 Free PMC article.
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