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Regulation of the metastatic process by E-selectin and stress-activated protein kinase-2/p38.
Laferriere J, Houle F, Huot J. Laferriere J, et al. Among authors: huot j. Ann N Y Acad Sci. 2002 Nov;973:562-72. doi: 10.1111/j.1749-6632.2002.tb04702.x. Ann N Y Acad Sci. 2002. PMID: 12485930 Review.
Endothelial microRNAs regulating the NF-κB pathway and cell adhesion molecules during inflammation.
Zhong L, Simard MJ, Huot J. Zhong L, et al. Among authors: huot j. FASEB J. 2018 Aug;32(8):4070-4084. doi: 10.1096/fj.201701536R. Epub 2018 Mar 22. FASEB J. 2018. PMID: 29565737 Review.
The roles of secreted miRNAs as paracrine regulators, and cell adhesion molecule-based miRNA delivery are also addressed.-Zhong, L., Simard, M. J., Huot, J. Endothelial microRNAs regulating the NF-kappaB pathway and cell adhesion molecules during inflammation …
The roles of secreted miRNAs as paracrine regulators, and cell adhesion molecule-based miRNA delivery are also addressed.-Zhong, L., Simard, …
IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation.
Roussel L, Houle F, Chan C, Yao Y, Bérubé J, Olivenstein R, Martin JG, Huot J, Hamid Q, Ferri L, Rousseau S. Roussel L, et al. Among authors: huot j. J Immunol. 2010 Apr 15;184(8):4531-7. doi: 10.4049/jimmunol.0903162. Epub 2010 Mar 12. J Immunol. 2010. PMID: 20228195
Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3.
Porquet N, Poirier A, Houle F, Pin AL, Gout S, Tremblay PL, Paquet ER, Klinck R, Auger FA, Huot J. Porquet N, et al. Among authors: huot j. BMC Cancer. 2011 Jul 1;11:285. doi: 10.1186/1471-2407-11-285. BMC Cancer. 2011. PMID: 21722370 Free PMC article.
p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells.
Zhong L, Huot J, Simard MJ. Zhong L, et al. Among authors: huot j. Sci Rep. 2018 Feb 5;8(1):2334. doi: 10.1038/s41598-018-20837-9. Sci Rep. 2018. PMID: 29402939 Free PMC article.
The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells.
Corre I, Paris F, Huot J. Corre I, et al. Among authors: huot j. Oncotarget. 2017 May 29;8(33):55684-55714. doi: 10.18632/oncotarget.18264. eCollection 2017 Aug 15. Oncotarget. 2017. PMID: 28903453 Free PMC article. Review.
Regulation of endothelial permeability and transendothelial migration of cancer cells by tropomyosin-1 phosphorylation.
Simoneau B, Houle F, Huot J. Simoneau B, et al. Among authors: huot j. Vasc Cell. 2012 Nov 17;4(1):18. doi: 10.1186/2045-824X-4-18. Vasc Cell. 2012. PMID: 23157718 Free PMC article.
Annexin-1-mediated endothelial cell migration and angiogenesis are regulated by vascular endothelial growth factor (VEGF)-induced inhibition of miR-196a expression.
Pin AL, Houle F, Fournier P, Guillonneau M, Paquet ÉR, Simard MJ, Royal I, Huot J. Pin AL, et al. Among authors: huot j. J Biol Chem. 2012 Aug 31;287(36):30541-51. doi: 10.1074/jbc.M112.393561. Epub 2012 Jul 6. J Biol Chem. 2012. PMID: 22773844 Free PMC article.
Role of cancer microenvironment in metastasis: focus on colon cancer.
Gout S, Huot J. Gout S, et al. Among authors: huot j. Cancer Microenviron. 2008 Dec;1(1):69-83. doi: 10.1007/s12307-008-0007-2. Epub 2008 Mar 14. Cancer Microenviron. 2008. PMID: 19308686 Free PMC article.
Endothelial cell migration during angiogenesis.
Lamalice L, Le Boeuf F, Huot J. Lamalice L, et al. Among authors: huot j. Circ Res. 2007 Mar 30;100(6):782-94. doi: 10.1161/01.RES.0000259593.07661.1e. Circ Res. 2007. PMID: 17395884 Review.
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